Boronate ester (BE) hydrogels are increasingly used for biomedical applications. The
dynamic nature of these molecular networks enables bond rearrangement, which is …

There is increasing evidence that cancer progression is linked to tissue viscoelasticity, which
challenges the commonly accepted notion that stiffness is the main mechanical hallmark of …

The tumor microenvironment (TME) in pancreatic adenocarcinoma (PDAC) is a complex
milieu of cellular and non-cellular components. Pancreatic cancer cells (PCC) and cancer …

Many recent reports have shown the effects of viscoelasticity of the extracellular matrix on
the spreading, migration, proliferation, survival and cell–matrix interaction of mesenchymal …

Transforming growth factor (TGF)‐β1 is a multifunctional cytokine that plays important roles
in health and disease. Previous studies have revealed that TGFβ1 activation, signaling, and …

The dynamic interplay between cells and their native extracellular matrix (ECM) influences
cellular behavior, imposing a challenge in biomaterial design. Dynamic covalent hydrogels …

The mechanics of the tumor microenvironment (TME) significantly impact disease
progression and the efficacy of anti-cancer therapeutics. While it is recognized that …

The understanding of cancer has evolved significantly, with the tumor microenvironment
(TME) now recognized as a critical factor influencing the onset and progression of the …

The pancreas is a glandular organ that maintains internal homeostasis through its endocrine
and exocrine functions. These functions are vital for overall well-being. However …

Metastasis is one of the greatest challenges in cancer treatment today. Normal mammary
epithelial cells are optimally supported by interaction with a soft matrix (microenvironment) …