The current United States Environmental Protection Agency (EPA) classification of di (2-
ethylhexyl) phthalate (DEHP) as a B2 “probable human” carcinogen is based on outdated …

Acrylamide (ACR) is used in the manufacture of polyacrylamides and has recently been
shown to form when foods, typically containing certain nutrients, are cooked at normal …

A Lifetime Oncogenicity Study in Rats with Acrylamide. Friedman, MA, Dulak, LH, and
Stedham, MA (1995). Fundam. Appl. Toxicol. 27, 95-105. A lifetime oncogenicity study in …

Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second
Edition is a practical guide to the common statistical problems encountered in toxicology and …

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLYWorking in the
laboratory or office, you use a diverse assortment of basic information to design, conduct …

Prostate tissues obtained from rats given a food-derived carcinogen, 2-amino-1-methyl-6-
phenylimidazo [4, 5-b] pyridine (PhIP), at a dose of 400 ppm in the diet for 52 weeks were …

Abstract The plasticizer di (2-ethylhexyl) phthalate (DEHP), to which humans are extensively
exposed, was found to be hepatocarcinogenic in rats and mice. DEHP is potentially set free …

Spontaneous neoplasm rates were determined for control Fischer 344 (F344) rats and
B6C3F, mice from 2-yr rodent carcinogenicity studies carried out by the National Toxicology …

This paper considers the use of historical control data in the evaluation of tumor incidences
from carcinogenicity studies in rodents. Although the most appropriate control group for …

Male and femal F344 rats were exposed 7 hr/day, 5 day/week for up to 30 months to
automotive diesel engine exhaust at soot concentrations of 0.35, 3.5, or 7.0 mg/m 3 or were …