Increasing evidence indicates that non-DNA sequence-based epigenetic information can be
inherited across several generations in organisms ranging from yeast to plants to humans …

Animals transmit not only DNA but also other molecules, such as RNA, proteins and
metabolites, to their progeny via gametes. It is currently unclear to what extent these …

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
creates a significant threat to global health. Recent studies suggested the significance of …

The idea that epigenetic determinants such as DNA methylation, histone modifications or
RNA can be passed to the next generation through meiotic products (gametes) is long …

A guiding principle of biology is that biochemical reactions must be organized in space and
time. One way this spatio-temporal organization is achieved is through liquid–liquid phase …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …

Evidence from animal studies and human famines suggests that starvation may affect the
health of the progeny of famished individuals. However, it is not clear whether starvation …

Transgenerational effects have wide-ranging implications for human health, biological
adaptation, and evolution; however, their mechanisms and biology remain poorly …

Heritability has traditionally been thought to be a characteristic feature of the genetic
material of an organism—notably, its DNA. However, it is now clear that inheritance not …

This review describes new developments in the study of transgenerational epigenetic
inheritance, a component of epigenetics. We start by examining the basic concepts of the …