Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
CCL13 and human diseases
L Li, F Dai, L Wang, Y Sun, L Mei, Y Ran… - Frontiers in …, 2023 - frontiersin.org
CCL13/MCP-4 belongs to the CC chemokine family, which induces chemotaxis in many
immune cells. Despite extensive research into its function in numerous disorders, a thorough …
immune cells. Despite extensive research into its function in numerous disorders, a thorough …
Omics technologies in allergy and asthma research: An EAACI position paper
U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …
several distinct complex endotypes. Both environmental and genetic factors can influence …
[HTML][HTML] The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
Since the 1960 s, our health has been compromised by exposure to over 350,000 newly
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …
Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the …
F Roth‐Walter, IM Adcock, C Benito‐Villalvilla… - Allergy, 2024 - Wiley Online Library
The accumulation of senescent cells drives inflammaging and increases morbidity of chronic
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …
Emerging roles of platelets in allergic asthma
M Yue, M Hu, F Fu, H Ruan, C Wu - Frontiers in Immunology, 2022 - frontiersin.org
Allergic asthma is a complex chronic inflammatory disease of the airways, driven by Th2
immune responses and characterized by eosinophilic pulmonary inflammation, airway …
immune responses and characterized by eosinophilic pulmonary inflammation, airway …
Deciphering the role of platelets in severe allergy by an integrative omics approach
C Pablo‐Torres, E Izquierdo, TJ Tan, D Obeso… - Allergy, 2023 - Wiley Online Library
Background Mechanisms causing the onset and perpetuation of inflammation in severe
allergic patients remain unknown. Our previous studies suggested that severe allergic …
allergic patients remain unknown. Our previous studies suggested that severe allergic …
Leukocyte redistribution as immunological biomarker of corticosteroid resistance in severe asthma
C Cardoso‐Vigueros, T von Blumenthal… - Clinical & …, 2022 - Wiley Online Library
Background Earlier studies have suggested that the leukocyte redistribution can be
considered as an immunological marker of the clinical response to corticosteroids (CS) …
considered as an immunological marker of the clinical response to corticosteroids (CS) …
AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI‐EANO position paper
MC Turner, U Radzikowska, DE Ferastraoaru… - Allergy, 2024 - Wiley Online Library
Epidemiological studies have explored the relationship between allergic diseases and
cancer risk or prognosis in AllergoOncology. Some studies suggest an inverse association …
cancer risk or prognosis in AllergoOncology. Some studies suggest an inverse association …
Transcriptomics reveals a distinct metabolic profile in T cells from severe allergic asthmatic patients
C Pablo-Torres, C Garcia-Escribano, M Romeo… - Frontiers in …, 2023 - frontiersin.org
The reasons behind the onset and continuation of chronic inflammation in individuals with
severe allergies are still not understood. Earlier findings indicated that there is a connection …
severe allergies are still not understood. Earlier findings indicated that there is a connection …