Noncoding RNA: RNA regulatory networks in cancer

JJ Chan, Y Tay - International journal of molecular sciences, 2018 - mdpi.com
Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …

Long noncoding RNAs in cancer: from discovery to therapeutic targets

R Choudhari, MJ Sedano, AL Harrison… - Advances in clinical …, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …

Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

J Chen, Y Yu, H Li, Q Hu, X Chen, Y He, C Xue, F Ren… - Molecular cancer, 2019 - Springer
Background The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an
oncogenic regulator of several cancers. However, its expression and function in gallbladder …

Identification of the 3-lncRNA signature as a prognostic biomarker for colorectal cancer

S Liu, Q Cao, G An, B Yan, L Lei - International journal of molecular …, 2020 - mdpi.com
Colorectal cancer (CRC) is one of the most common malignant carcinomas in the world, and
metastasis is the main cause of CRC-related death. However, the molecular network …

[HTML][HTML] Long noncoding RNA CRNDE promotes multiple myeloma cell growth by suppressing miR-451

YB Meng, X He, YF Huang, QN Wu, YC Zhou… - Oncology …, 2017 - ncbi.nlm.nih.gov
It has been determined that long noncoding RNAs (lncRNAs) are identified as a potential
regulatory factor in multiple tumors as well as multiple myeloma (MM). However, the role of …

[PDF][PDF] RETRACTED: The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis

C Yang, J Zheng, Y Xue, H Yu, X Liu, J Ma… - Frontiers in Molecular …, 2018 - frontiersin.org
Glioblastoma (GBM) is the most aggressive and malignant primary tumor. Angiogenesis
plays a critical role in the progression of GBM. Previous studies have indicated that long non …

LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

Y Xu, Y Li, J Jin, G Han, C Sun, MP Pizzi, L Huo… - Molecular cancer, 2019 - Springer
Background PVT1 has emerged as an oncogene in many tumor types. However, its role in
Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) is unknown. The aim of …

Long noncoding RNA PVT1 promotes EMT via mediating microRNA-186 targeting of Twist1 in prostate cancer

Z Chang, J Cui, Y Song - Gene, 2018 - Elsevier
The pathogenesis and the underlying mechanism of endothelial-mesenchymal transition in
prostate cancer remain unclear. Plasmacytoma variant translocation 1 (PVT1), a novel long …

Interactions between short and long noncoding RNAs

I Ulitsky - FEBS letters, 2018 - Wiley Online Library
It is now evident that noncoding RNAs play key roles in regulatory networks determining cell
fate and behavior, in a myriad of different conditions, and across all species. Among these …

The role of lncRNAs in the distant metastasis of breast cancer

Y Wu, A Shao, L Wang, K Hu, C Yu, C Pan… - Frontiers in …, 2019 - frontiersin.org
Breast cancer (BC) remains the most frequently diagnosed cancer worldwide. Among breast
cancer patients, distant metastasis and invasion is the leading cause of BC related death …