The active template approach to interlocked molecules takes advantage of the ability of
metal ions to both organize precursor fragments for mechanical bond formation and to …

More than a quarter of a century after the first metal template synthesis of a [2] catenane in
Strasbourg, there now exists a plethora of strategies available for the construction of …

The active template synthesis of mechanically interlocked molecular architectures exploits
the dual ability of various structural elements (metals or, in the case of metal-free active …

A growing variety of covalent reactions have been employed to achieve the post-assembly
modification (PAM) of self-assembled metallosupramolecular complexes. Covalent PAM …

Rotaxanes are molecules composed of one or more macrocycles threaded onto one or more
axles that bear bulky stoppers to prevent the macrocycles from slipping off. 1 The first …

We describe the first method for production of mechanically planar chiral rotaxanes in
excellent enantiopurity without the use of chiral separation techniques and, for the first time …

In this article, we proved that all three key steps in the catalytic cycle of CuAAC can proceed
in the presence of carboxylic acids and the latter two steps can be promoted significantly by …

By shrinking the macrocycle in the CuAAC active template reaction not only is it
demonstrated to be possible to use smaller macrocycles, but, surprisingly, that smaller …

Chiral interlocked molecules in which the mechanical bond provides the sole stereogenic
unit are typically produced with no control over the mechanical stereochemistry. Here we …

Although many different approaches to catenanes and rotaxanes have been introduced,[1]
few strategies have been successfully developed for the synthesis of molecular knots.[2] …