SARS-CoV-2-specific T cells exhibit phenotypic features of helper function, lack of terminal differentiation, and high proliferation potential
Summary Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …
Temporal dynamics and heterogeneity of cell populations during skeletal muscle regeneration
Mammalian skeletal muscle possesses a unique ability to regenerate, which is primarily
mediated by a population of resident muscle stem cells (MuSCs) and requires a concerted …
mediated by a population of resident muscle stem cells (MuSCs) and requires a concerted …
Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir
The latent reservoir is a major barrier to HIV cure. As latently infected cells cannot be
phenotyped directly, the features of the in vivo reservoir have remained elusive. Here, we …
phenotyped directly, the features of the in vivo reservoir have remained elusive. Here, we …
Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency
S Telwatte, S Lee, MA Somsouk, H Hatano… - PLoS …, 2018 - journals.plos.org
Latently-infected CD4+ T cells are widely considered to be the major barrier to a cure for
HIV. Much of our understanding of HIV latency comes from latency models and blood cells …
HIV. Much of our understanding of HIV latency comes from latency models and blood cells …
Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner
MR Fazazi, PMIA Doss, R Pereira, N Fudge… - Nature …, 2024 - nature.com
B cells and T cells collaborate in multiple sclerosis (MS) pathogenesis. IgH [MOG] mice
possess a B cell repertoire skewed to recognize myelin oligodendrocyte glycoprotein …
possess a B cell repertoire skewed to recognize myelin oligodendrocyte glycoprotein …
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection
The primary reservoir for HIV is within memory CD4+ T cells residing within tissues, yet the
features that make some of these cells more susceptible than others to infection by HIV is not …
features that make some of these cells more susceptible than others to infection by HIV is not …
Inside the joint of inflammatory arthritis patients: handling and processing of synovial tissue biopsies for high throughput analysis
Inflammatory arthritis is a chronic systemic autoimmune disease of unknown etiology, which
affects the joints. If untreated, these diseases can have a detrimental effect on the patient's …
affects the joints. If untreated, these diseases can have a detrimental effect on the patient's …
[HTML][HTML] ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV
Novel therapeutic strategies are needed to attenuate increased systemic and gut
inflammation that contribute to morbidity and mortality in chronic HIV infection despite potent …
inflammation that contribute to morbidity and mortality in chronic HIV infection despite potent …
SARS-CoV-2-specific T cells exhibit unique features characterized by robust helper function, lack of terminal differentiation, and high proliferative potential
Convalescing COVID-19 patients mount robust T cell responses against SARS-CoV-2,
suggesting an important role for T cells in viral clearance. To date, the phenotypes of SARS …
suggesting an important role for T cells in viral clearance. To date, the phenotypes of SARS …
Duodenal CD8+ T resident memory cell apoptosis contributes to gut barrier dysfunction and microbial translocation in early alcohol‐associated liver disease in …
L Maccioni, A Loriot, J Dewulf… - Alimentary …, 2022 - Wiley Online Library
Background Intestinal T cells are key in gut barrier function. Their role in early stages of
alcohol‐associated liver disease (ALD) remain unknown. Aim To explore the links between …
alcohol‐associated liver disease (ALD) remain unknown. Aim To explore the links between …