Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics
A Kirtonia, K Gala, SG Fernandes, G Pandya… - Seminars in cancer …, 2021 - Elsevier
Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
The renin–angiotensin system and cancer: old dog, new tricks
For cancers to develop, sustain and spread, the appropriation of key homeostatic
physiological systems that influence cell growth, migration and death, as well as …
physiological systems that influence cell growth, migration and death, as well as …
Cardiovascular disease and cancer: evidence for shared disease pathways and pharmacologic prevention
Cardiovascular disease (CVD) and cancer are leading causes of mortality and morbidity
worldwide. Strategies to improve their treatment and prevention are global priorities and …
worldwide. Strategies to improve their treatment and prevention are global priorities and …
Repurposing drugs targeting metabolic diseases for cancer therapeutics
Highlights•Discovery of new drugs against cancer is of utmost importance.•Drug repurposing
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …
Anticancer potential of animal venoms and toxins
A Gomes, P Bhattacharjee, R Mishra, AK Biswas… - 2010 - nopr.niscpr.res.in
Anticancer drug development from natural resources are ventured throughout the world.
Animal venoms and toxins a potential bio resource and a therapeutic tool were known to …
Animal venoms and toxins a potential bio resource and a therapeutic tool were known to …
[HTML][HTML] CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline …
RE Kast, G Karpel-Massler, ME Halatsch - Oncotarget, 2014 - ncbi.nlm.nih.gov
CUSP9 treatment protocol for recurrent glioblastoma was published one year ago. We now
present a slight modification, designated CUSP9*. CUSP9* drugs-aprepitant, artesunate …
present a slight modification, designated CUSP9*. CUSP9* drugs-aprepitant, artesunate …
Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer …
S Wilop, S von Hobe, M Crysandt, A Esser… - Journal of cancer …, 2009 - Springer
Purpose The renin-angiotensin system plays a crucial role in maintaining vascular
homeostasis. Stimulation of angiotensin II type 1 receptors (AT1R) acts proangiogenically by …
homeostasis. Stimulation of angiotensin II type 1 receptors (AT1R) acts proangiogenically by …
Repurposing of chronically used drugs in cancer therapy: a chance to grasp
MA Hijazi, A Gessner, N El-Najjar - Cancers, 2023 - mdpi.com
Simple Summary Cancer mortalities are growing at an alarming pace around the globe, a
fact related to challenges, such as side effects, selectivity, and resistance, accompanied by …
fact related to challenges, such as side effects, selectivity, and resistance, accompanied by …
The angiotensin-converting enzyme 2 in tumor growth and tumor-associated angiogenesis in non-small cell lung cancer
Y Feng, H Wan, J Liu, R Zhang, Q Ma… - Oncology …, 2010 - spandidos-publications.com
Angiotensin II (AngII) is a multifunctional bioactive peptide and previous studies have shown
that the renin-angiotensin system (RAS) of both host and tumor are important in tumor …
that the renin-angiotensin system (RAS) of both host and tumor are important in tumor …
Renin-angiotensin system in lung tumor and microenvironment interactions
MJ Catarata, R Ribeiro, MJ Oliveira, C Robalo Cordeiro… - Cancers, 2020 - mdpi.com
The mechanistic involvement of the renin-angiotensin system (RAS) reaches beyond
cardiovascular physiopathology. Recent knowledge pinpoints a pleiotropic role for this …
cardiovascular physiopathology. Recent knowledge pinpoints a pleiotropic role for this …