Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

For cancers to develop, sustain and spread, the appropriation of key homeostatic
physiological systems that influence cell growth, migration and death, as well as …

Cardiovascular disease (CVD) and cancer are leading causes of mortality and morbidity
worldwide. Strategies to improve their treatment and prevention are global priorities and …

Highlights•Discovery of new drugs against cancer is of utmost importance.•Drug repurposing
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …

Anticancer drug development from natural resources are ventured throughout the world.
Animal venoms and toxins a potential bio resource and a therapeutic tool were known to …

CUSP9 treatment protocol for recurrent glioblastoma was published one year ago. We now
present a slight modification, designated CUSP9*. CUSP9* drugs-aprepitant, artesunate …

Purpose The renin-angiotensin system plays a crucial role in maintaining vascular
homeostasis. Stimulation of angiotensin II type 1 receptors (AT1R) acts proangiogenically by …

Simple Summary Cancer mortalities are growing at an alarming pace around the globe, a
fact related to challenges, such as side effects, selectivity, and resistance, accompanied by …

Angiotensin II (AngII) is a multifunctional bioactive peptide and previous studies have shown
that the renin-angiotensin system (RAS) of both host and tumor are important in tumor …

The mechanistic involvement of the renin-angiotensin system (RAS) reaches beyond
cardiovascular physiopathology. Recent knowledge pinpoints a pleiotropic role for this …