Background Dental caries is a chronic, multifactorial and biofilm-mediated oral bacterial
infection affecting almost every age group and every geographical region. Streptococcus …

Bacterial stress can be defined as any change in conditions resulting in a deviation from the
ideal growth rate of a bacterium. Hence, there is a continuum of stresses ranging in severity …

The accumulation of cadmium (Cd) in rice grains is closely associated with the content of
mineral nutrients and amino acid metabolism, but the causal link among them is unclear …

Abstract Calcium (Ca 2+) is a universal signaling ion, whose major informational role
shaped the evolution of signaling pathways, enabling cellular communications and …

Streptococcus mutans (S. mutans) is generally regarded as a major contributor to dental
caries because of its ability to synthesize extracellular polysaccharides (EPS) that aid in the …

The VicRK 2-component system of Streptococcus mutans regulates genes associated with
cell wall biogenesis and biofilm formation. A putative RNase III–encoding gene (rnc) is …

We present an overview of how members of the oral microbiota respond to their environment
by regulating gene expression through two-component signal transduction systems (TCSs) …

Functional protein-protein interactions are crucial in most cellular processes. They enable
multi-protein complexes to assemble and to remain stable, and they allow signal …

Oral microecological balance is closely associated with the development of dental caries.
Oxidative stress is one of the important factors regulating the composition and structure of …

Two-component signaling systems (TCSs) are composed of two proteins, sensor kinases
and response regulators, which can cross-talk and integrate information between them by …