Synthesis strategies and medicinal value of pyrrole and its fused heterocyclic compounds
SS Fatahala, MS Mohamed, JY Sabry… - Medicinal …, 2022 - benthamdirect.com
In the last several decades, interest in pyrrole and pyrrolopyrimidine derivatives has
increased owing to their biological importance, such as anti-tumor, anti-microbial, anti …
increased owing to their biological importance, such as anti-tumor, anti-microbial, anti …
Pyrrole: An Essential Framework in the Development of Therapeutic Agents and Insightful Analysis of Structure‐Active Relationships
B Sahu, R Sahu, B Gidwani, A Mishra - ChemistrySelect, 2024 - Wiley Online Library
Pyrrole is a heterocyclic structure with diverse pharmacophores, enabling the creation of an
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …
In vitro and in silico exploration of newly synthesized triazolyl- isonicotinohydrazides as potent antitubercular agents
RD Bakale, PS Phatak, SS Rathod… - Journal of …, 2023 - Taylor & Francis
In the present study, we have reported the synthesis of novel isoniazid-triazole derivatives
(4a-r), via the click chemistry approach. The synthesized isoniazid-triazole derivatives have …
(4a-r), via the click chemistry approach. The synthesized isoniazid-triazole derivatives have …
A new series of asymmetric bis-isatin derivatives containing urea/thiourea moiety: Preparation, spectroscopic elucidation, antioxidant properties and theoretical …
In the present study, design, synthesis, characterization, and investigation of antioxidant
properties of novel asymmetric bis-isatin derivatives (1-8) containing urea/thiourea moiety …
properties of novel asymmetric bis-isatin derivatives (1-8) containing urea/thiourea moiety …
Screening of potent α‐glucosidase inhibitory and antioxidant polyphenols in Prunella vulgaris L. by bioreaction–HPLC–quadrupole‐time‐of‐flight‐MS/MS and in …
L Cheng, F Wang, Y Cao, G Cai, Q Wei… - Journal of …, 2022 - Wiley Online Library
Prunella vulgaris L. is a well‐known traditional Chinese medicine for blood glucose
homeostasis and antioxidant potential. Ethyl acetate fraction of P. vulgaris L. demonstrated …
homeostasis and antioxidant potential. Ethyl acetate fraction of P. vulgaris L. demonstrated …
Relationship between antioxidant activity and ESIPT process based on flavonoid derivatives: A comprehensive analysis
X Tang, L Wang, Y Zhang, C Sun - … Acta Part A: Molecular and Biomolecular …, 2025 - Elsevier
Antioxidant activity, as a topic of current interest, is discussed together with the excited state
intramolecular proton transfer (ESIPT) process for three flavonoid derivatives, based on …
intramolecular proton transfer (ESIPT) process for three flavonoid derivatives, based on …
Activation of xanthine oxidase by 1, 4-naphthoquinones: A novel potential research topic for diet management and risk assessment
S Liang, L Liu, B He, W Zhao, W Zhang, L Xiao… - Food Chemistry, 2023 - Elsevier
Abstract Oral intake of 1, 4-naphthoquinones could be a potential risk factor for
hyperuricemia and gout via activation of xanthine oxidase (XO). Herein, 1, 4 …
hyperuricemia and gout via activation of xanthine oxidase (XO). Herein, 1, 4 …
Structure–antioxidant activity relationships of dendrocandin analogues determined using density functional theory
N Zhang, Y Wu, M Qiao, W Yuan, X Li, X Wang… - Structural Chemistry, 2022 - Springer
Quantum-chemical calculations based on the density functional theory (DFT) at the B3LYP/6–
311++ G (2d, 2p)//B3LYP/6–31G (d, p) level were employed to study the relationship …
311++ G (2d, 2p)//B3LYP/6–31G (d, p) level were employed to study the relationship …
Clauson–Kaas pyrrole synthesis using diverse catalysts: a transition from conventional to greener approach
Pyrrole is an important aromatic heterocyclic scaffold found in many natural products and
predominantly used in pharmaceuticals. Continuous efforts are being made to design and …
predominantly used in pharmaceuticals. Continuous efforts are being made to design and …
[HTML][HTML] Multi-component synthesis and invitro biological assessment of novel pyrrole derivatives and pyrano[2,3-c]pyrazole derivatives using Co3O4 nanoparticles …
TM Almeleebia, M Jasim Naser, SM Saeed… - Frontiers in …, 2024 - frontiersin.org
In this study, Co3O4 nanoparticles were used as nanocatalyst for two different series of
nitrogen-containing heterocyclic compounds, including pyrrole (Pyo) derivatives and pyrano …
nitrogen-containing heterocyclic compounds, including pyrrole (Pyo) derivatives and pyrano …