Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation

AMA Rokstad, I Lacik, P de Vos, BL Strand - Advanced drug delivery …, 2014 - Elsevier
Cell encapsulation has already shown its high potential and holds the promise for future cell
therapies to enter the clinics as a large scale treatment option for various types of diseases …

Mesenchymal stem cell 3D encapsulation technologies for biomimetic microenvironment in tissue regeneration

H Kim, C Bae, YM Kook, WG Koh, K Lee… - Stem cell research & …, 2019 - Springer
Mesenchymal stem cell (MSC) encapsulation technique has long been emerged in tissue
engineering as it plays an important role in implantation of stem cells to regenerate a …

The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells

GA Salg, NA Giese, M Schenk… - Journal of tissue …, 2019 - journals.sagepub.com
A bioartificial endocrine pancreas is proposed as a future alternative to current treatment
options. Patients with insulin-secretion deficiency might benefit. This is the first systematic …

Therapeutic cell encapsulation techniques and applications in diabetes

JAM Steele, JP Hallé, D Poncelet, RJ Neufeld - Advanced drug delivery …, 2014 - Elsevier
The encapsulation of therapeutic cells permits the implantation of allogeneic and
xenogeneic cells for the regulation of certain physiological processes damaged by the death …

The bioartificial pancreas (BAP): Biological, chemical and engineering challenges

V Iacovacci, L Ricotti, A Menciassi, P Dario - Biochemical pharmacology, 2016 - Elsevier
The bioartificial pancreas (BAP) represents a viable solution for the treatment of type 1
diabetes (T1D). By encapsulating pancreatic cells in a semipermeable membrane to allow …

Islet microencapsulation: strategies and clinical status in diabetes

M Omami, JJ McGarrigle, M Reedy, D Isa, S Ghani… - Current diabetes …, 2017 - Springer
Abstract Purpose of Review Type 1 diabetes mellitus (T1DM) is an autoimmune disease that
results from the destruction of insulin-producing pancreatic β cells in the islets of …

[HTML][HTML] Chemical strategies for improving islet transplant outcomes

JM Quintana, AL Stinchcomb, JH Kostyo… - OBM …, 2018 - lidsen.com
Islet transplantation has proven to be a viable treatment for individuals suffering from both
Type 1 Diabetes Mellitus (T1D) and chronic pancreatitis. However, a variety of challenges …

Molecular imaging of pancreatic islet transplantation

Y Liu, B Song, X Ran, Q Jiang, J Hu… - Experimental and …, 2014 - thieme-connect.com
Islet replacement therapy, pancreatic islet transplantation, is considered as a potential
option for curing T1DM. However, the significant loss of implanted islets after islet …

Current status on immunoprotection of transplanted islets: focus on islet microencapsulation

I Lacík - Micro and Nanosystems, 2013 - ingentaconnect.com
This minireview focuses on recent developments in the field of islet microencapsulation as
one of the strategies for immunoprotection of transplanted insulin-producing cells for future …

Investigating design principles of micropatterned encapsulation systems containing high-density microtissue arrays

LY Jiang, JY Liu, K Wang, X Gu, Y Luo - Science China Life sciences, 2014 - Springer
Immunoisolation is an important strategy to protect transplanted cells from rejection by the
host immune system. Recently, microfabrication techniques have been used to create …