Mammalian epidermis is renewed throughout life by proliferation of a multipotential stem cell
population and terminal differentiation of stem cell progeny. In recent years, extracellular …

The maintenance of a healthy corneal epithelium under both normal and wound healing
conditions is achieved by a population of stem cells (SC) located in the basal epithelium at …

This study evaluated proposed molecular markers related to stem cell (SC) properties with
the intention of characterizing a putative SC phenotype in human limbal epithelia. Human …

One of the important functions of the cornea is to maintain normal vision by refracting light
onto the lens and retina. This property is dependent in part on the ability of the corneal …

Among all adult somatic stem cells, those of the corneal epithelium are unique in their
exclusive location in a defined limbal structure termed Palisades of Vogt. As a result …

PURPOSE: To evaluate the efficacy of multilayer amniotic membrane transplantation for
reconstruction of corneal epithelium and stroma in the context of deep corneal ulcers …

Members of the integrin family of adhesion receptors mediate both cell-cell and cell-matrix
interactions and have been shown to play vital roles in embryonic development, wound …

Osteopontin is an adhesive glycoprotein implicated in numerous diseases associated with
inflammation and remodeling. There are several structural domains in osteopontin that are …

The development of the cornea as a tissue initiates as early as five weeks in the human
embryo. This development continues gradually until the time of eyelid opening, which is …

In human corneal epithelium, self-renewal and fate decision of stem cells are highly
regulated in a niche microenvironment called palisades of Vogt in the limbus. Herein, we …