Heated humidified high-flow nasal oxygen in adults

G Spoletini, M Alotaibi, F Blasi, NS Hill - Chest, 2015 - Elsevier
Traditionally, nasal oxygen therapy has been delivered at low flows through nasal cannulae.
In recent years, nasal cannulae designed to administer heated and humidified air/oxygen …

A review of arterial phantom fabrication methods for flow measurement using PIV techniques

SG Yazdi, PH Geoghegan, PD Docherty… - Annals of Biomedical …, 2018 - Springer
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
western world. In the last three decades, fluid dynamics investigations have been an …

A physiological study to determine the mechanism of carbon dioxide clearance during apnoea when using transnasal humidified rapid insufflation ventilatory …

LA Hermez, CJ Spence, MJ Payton, SAR Nouraei… - …, 2019 - Wiley Online Library
Clinical observations suggest that compared with standard apnoeic oxygenation, transnasal
humidified rapid‐insufflation ventilatory exchange using high‐flow nasal oxygenation …

In vitro–in vivo correlation of intranasal drug deposition

S Le Guellec, S Ehrmann, L Vecellio - Advanced Drug Delivery Reviews, 2021 - Elsevier
In vitro–in vivo correlation (IVIVC) allows prediction of in vivo drug deposition from a nasally
inhaled drug based on in vitro drug measurements. In vitro measurements include physical …

Fabrication of rigid and flexible refractive-index-matched flow phantoms for flow visualisation and optical flow measurements

PH Geoghegan, NA Buchmann, CJT Spence… - Experiments in …, 2012 - Springer
A method for the construction of both rigid and compliant (flexible) transparent flow
phantoms of biological flow structures, suitable for PIV and other optical flow methods with …

Investigation of inhalation and exhalation flow pattern in a realistic human upper airway model by PIV experiments and CFD simulations

X Xu, J Wu, W Weng, M Fu - Biomechanics and modeling in …, 2020 - Springer
In this study, flow field characteristics in the trachea region in a realistic human upper airway
model were firstly measured by particle image velocimetry (PIV) in the air under three …

Recent options and techniques to assess improved bioavailability: In vitro and ex vivo methods

L Józsa, D Nemes, Á Pető, D Kósa, R Révész… - Pharmaceutics, 2023 - mdpi.com
Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Investigation of flow pattern in upper human airway including oral and nasal inhalation by PIV and CFD

NL Phuong, K Ito - Building and Environment, 2015 - Elsevier
Breathing is one of the most essential processes in the human body. The basic functions of
breathing are to exchange gases (supplying oxygen from ambient air and removing carbon …

Review of computational fluid dynamics in the assessment of nasal air flow and analysis of its limitations

M Quadrio, C Pipolo, S Corti, R Lenzi… - European archives of …, 2014 - Springer
Nasal breathing difficulties (NBD) are a widespread medical condition, yet decisions
pertaining to the surgical treatment of chronic NBD still imply a significant degree of …

Unsteady flow in the nasal cavity with high flow therapy measured by stereoscopic PIV

CJT Spence, NA Buchmann, MC Jermy - Experiments in fluids, 2012 - Springer
Nasal high flow (NHF) cannulae are used to deliver heated and humidified air to patients at
steady flows ranging from 5 to 50 l/min. In this study, the flow velocities in the nasal cavity …