Nanopores in solid-state membranes are promising for a wide range of applications
including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data …

Nanopore sensors have received significant interest for the detection of clinically important
biomarkers with single-molecule resolution. These sensors typically operate by detecting …

Single-molecule measurements have greatly enhanced our understanding of living systems.
Biological systems offer nanopores, a sub-class of membrane proteins, the well-defined …

Nanopores are promising single-molecule tools for the electrical identification and
sequencing of biomolecules. However, the characterization of proteins, especially in real …

Protein conformations play crucial roles in most, if not all, biological processes. Here we
show that the current carried through a nanopore by ions allows monitoring conformational …

Biological nanopores are emerging as powerful tools for single-molecule analysis and
sequencing. Here, we engineered the two-component pleurotolysin (PlyAB) toxin to …

A fundamental question relating to protein folding/unfolding is the time evolution of the
folding of a protein into its precisely defined native structure. The proper identification of …

Outer membrane protein G (OmpG) is a monomeric porin found in Escherichia coli, which
possesses seven flexible loops. OmpG has been engineered as a nanopore sensor, where …

Protein nanopores have emerged as an important class of sensors for the understanding of
biophysical processes, such as molecular transport across membranes, and for the …

Resistive pulse nanopore sensing enables label‐free single‐molecule analysis of a wide
range of analytes. An increasing number of studies have demonstrated the feasibility and …