Obesity is a risk factor for developing type 2 diabetes and cardiovascular disease and has
quickly become a worldwide pandemic with few tangible and safe treatment options …

The Hepatic circulation is unique among vascular beds. The most obvious unique features
include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery …

The concept of autonomic balance views autonomic states along a bipolar continuum from
sympathetic (S) to parasympathetic (P) dominance, whereas regulatory capacity models …

The liver is innervated by both the sympathetic and the parasympathetic nerve systems.
These nerves are derived from the splanchnic and vagal nerves that surround the portal …

Rapamycin (RAPA), an immunosuprpressive drug used extensively to prevent graft rejection
in transplant patients, has been reported to inhibit adipogenesis in vitro. In this study, we …

Brain microvascular endothelial cells (BMECs) dysfunction is related to the pathogenesis of
neurovascular complication of diabetes mellitus that adversely lead to various CNS …

Background: Although impaired cardiac autonomic function is associated with an increased
risk of type 2 diabetes in Caucasians, evidence in Asian populations with a lower body mass …

The hepatic nervous system has a well-known impact on the regulation of liver function and
organism homeostasis. The aim of this review is to summarize the new available data …

Aims/hypothesis A considerable proportion of whole-body insulin-stimulated glucose uptake
is dependent upon the hepatic insulin-sensitising substance (HISS) in a pathway mediated …

Ethanol has been considered as a lifestyle factor that may influence the risk of type 2
diabetes mellitus. In healthy adults, acute ethanol consumption results in insulin resistance …