Mechanisms of acquired resistance to anti-VEGF therapy for neovascular eye diseases
D Sharma, I Zachary, H Jia - Investigative Ophthalmology & …, 2023 - iovs.arvojournals.org
Purpose: The purpose of this study was to evaluate clinical reports of response-loss in
patients with neovascular eye diseases, such as neovascular age-related macular …
patients with neovascular eye diseases, such as neovascular age-related macular …
Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review
CT Supuran - Expert Opinion on Therapeutic Patents, 2019 - Taylor & Francis
Introduction: Macular degeneration (MD) and macular edema (ME) are ophthalmologic
diseases affecting an increasing number of the aging population. Until recently, there were …
diseases affecting an increasing number of the aging population. Until recently, there were …
Intravitreal dexamethasone as a rescue for anti-vascular endothelial growth factor therapy in neovascular age-related macular degeneration with persistent disease …
M Pietzuch, I Mantel, A Ambresin… - Journal of Ocular …, 2024 - liebertpub.com
Purpose: To assess the impact of switching to, or adding, an intravitreal dexamethasone
implant (Dex; Ozurdex®) in anti-vascular endothelial growth factor (VEGF) therapy on …
implant (Dex; Ozurdex®) in anti-vascular endothelial growth factor (VEGF) therapy on …
Simultaneous Intravitreal Steroid and Anti-VEGF Therapy for Monotherapy-Resistant Chronic Wet Age-Related Macular Degeneration
Background and Objective: The purpose of this study was to analyze the safety and efficacy
of combined intravitreal anti-vascular endothelial growth factor (anti-VEGF) and steroid …
of combined intravitreal anti-vascular endothelial growth factor (anti-VEGF) and steroid …
Evaluation of the clinical utility of optical coherence tomography angiography in age-related macular degeneration
M Cavichini, KC Dans, M Jhingan… - British Journal of …, 2021 - bjo.bmj.com
Background/Aims To evaluate the ability of optical coherence tomography angiography
(OCTA) to identify the presence or absence of choroidal neovascularisation (CNV) and CNV …
(OCTA) to identify the presence or absence of choroidal neovascularisation (CNV) and CNV …
Short-Term Real-World Outcomes of Intensive Aflibercept Injection for Refractory Neovascular Age-Related Macular Degeneration
W Son, M Sagong - Journal of Clinical Medicine, 2024 - mdpi.com
Background: The aim of this study is to report short-term outcomes after the shortening of the
treatment interval to 4 weeks with a treat-and-extend (TAE) regimen (Si4w) of aflibercept in …
treatment interval to 4 weeks with a treat-and-extend (TAE) regimen (Si4w) of aflibercept in …
Understanding the half-life extension of intravitreally administered antibodies binding to ocular albumin
S Hauri, P Jakubiak, M Fueth, S Dengl, S Belli… - Pharmaceutics, 2020 - mdpi.com
The burden associated with frequent injections of current intravitreal (IVT) therapeutics may
be reduced by long-acting delivery strategies. Binding to serum albumin has been shown to …
be reduced by long-acting delivery strategies. Binding to serum albumin has been shown to …
Monthly Alternating Injections of Aflibercept and Bevacizumab for Neovascular Age-Related Macular Degeneration
J Lee, YN Kim, JG Kim - Journal of Clinical Medicine, 2022 - mdpi.com
We investigated the efficacy of monthly alternating injections of aflibercept and bevacizumab
(MAAB) for maintenance treatment in patients with neovascular age-related macular …
(MAAB) for maintenance treatment in patients with neovascular age-related macular …
[HTML][HTML] The Role of TNF-α Inhibitors in Managing Wet AMD
C Akotoye, P Shukla, RP Singh - retinalphysician.com
Age-related macular degeneration (AMD) is a multifactorial disease that exists in exudative
(wet) and nonexudative (dry) forms, with the former accounting for 80% of the legal …
(wet) and nonexudative (dry) forms, with the former accounting for 80% of the legal …