The development of heterocyclic derivatives has progressed considerably over the past few
decades, and many new agents of synthetic and natural origin have been produced. Among …

Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …

Based on the extensive biological activities of thiazole derivatives against different types of
diseases, we are interested in the effective part of many natural compounds, so we …

Microbial resistance is a big concern worldwide, making the development of new
antimicrobial drugs difficult. The thiazole and pyrazole rings are important heterocyclic …

Background: Thiazole is a good nucleus owing to its various pharmaceutical applications.
Thiazole containing compounds (thiazoles) have shown various biological activities like …

The synthesis and X-ray characterization of three new 4, 5-dihydropyrazolylthiazole–
coumarin hybrids (1–3) are reported herein, namely 3-(2-(3, 5-bis (4-chlorophenyl)-4, 5 …

The chemistry of 1, 3, 4-thiadiazole is one of the most interesting scaffolds for synthesizing
new drug molecules due to their numerous pharmacological activities. Several modifications …

Indane-1, 3-dione is a versatile building block used in numerous applications ranging from
biosensing, bioactivity, bioimaging to electronics or photopolymerization. In this review, an …

Herein, we report the design, synthesis, and evaluation of the antimicrobial activity of new
heteroaryl (aryl) thiazole derivatives. The design was based on a molecular hybridization …

Less than 5% of pancreatic cancer patients survive for more than five years after diagnosis.
Therefore, there is an urgent need for novel therapeutic drugs to treat pancreatic cancer …