Cleavage and polyadenylation (pA) is a fundamental step that is required for the maturation
of primary protein encoding transcripts into functional mRNAs that can be exported from the …

The RNA‐binding proteins encoded by the highly conserved elav/Hu gene family, found in
all metazoans, regulate the expression of a wide range of genes, at both the co …

Most eukaryotic genes express alternative polyadenylation (APA) isoforms with different 3′
UTR lengths, production of which is influenced by cellular conditions. Here, we show that …

Background The start and end sites of messenger RNAs (TSSs and TESs) are highly
regulated, often in a cell-type-specific manner. Yet the contribution of transcript diversity in …

Cellular stress causes multifaceted reactions to trigger adaptive responses to environmental
cues at all levels of the gene expression pathway. RNA-binding proteins (RBP) are key …

Alternative polyadenylation (APA) is a molecular mechanism during a pre‐mRNA
processing that involves usage of more than one polyadenylation site (PA‐site) generating …

The recent emergence of alternative polyadenylation (APA) as an engine driving
transcriptomic diversity has stimulated the development of sequencing methodologies …

Alternative polyadenylation (APA) is emerging as an important regulatory mechanism of
RNA and protein isoform expression by controlling 3′ untranslated region (3′-UTR) …

Aurora Kinase A (AURKA) is a positive regulator of mitosis with a strict cell cycle-dependent
expression pattern. Recently, novel oncogenic roles of AURKA have been uncovered that …

Alternative polyadenylation (APA) is a widespread mechanism that generates mRNA
isoforms with distinct properties. Here we have systematically mapped and compared …