Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system

N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

Resolution of inflammation: a new therapeutic frontier

JN Fullerton, DW Gilroy - Nature reviews Drug discovery, 2016 - nature.com
Dysregulated inflammation is a central pathological process in diverse disease states.
Traditionally, therapeutic approaches have sought to modulate the pro-or anti-inflammatory …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Gasotransmitters in cancer: from pathophysiology to experimental therapy

C Szabo - Nature reviews Drug discovery, 2016 - nature.com
The three endogenous gaseous transmitters—nitric oxide (NO), carbon monoxide (CO) and
hydrogen sulfide (H2S)—regulate a number of key biological functions. Emerging data have …

Mediators of the resolution of the inflammatory response

MA Sugimoto, JP Vago, M Perretti, MM Teixeira - Trends in immunology, 2019 - cell.com
The termination of inflammation is governed by endogenous molecules collectively referred
to as 'mediators of resolution'of inflammation. There is now strong evidence to suggest that …

The roles of microbial products in the development of colorectal cancer: a review

Y Fang, C Yan, Q Zhao, J Xu, Z Liu, J Gao, H Zhu… - …, 2021 - Taylor & Francis
ABSTRACT A large number of microbes exist in the gut and they have the ability to process
and utilize ingested food. It has been reported that their products are involved in colorectal …

H2S biosynthesis and catabolism: new insights from molecular studies

P Rose, PK Moore, YZ Zhu - Cellular and Molecular Life Sciences, 2017 - Springer
Hydrogen sulfide (H 2 S) has profound biological effects within living organisms and is now
increasingly being considered alongside other gaseous signalling molecules, such as nitric …

Real-time imaging of hepatic inflammation using hydrogen sulfide-activatable second near-infrared luminescent nanoprobes

Q Liu, Y Zhong, Y Su, L Zhao, J Peng - Nano Letters, 2021 - ACS Publications
The sensing and visualized monitoring of hydrogen sulfide (H2S) in vivo is crucial to
understand its physiological and pathological roles in human health and diseases. Common …

On-demand therapeutic delivery of hydrogen sulfide aided by biomolecules

Y Ge, F Rong, W Li, Y Wang - Journal of Controlled Release, 2022 - Elsevier
Abstract Hydrogen sulfide (H 2 S), known as the third gasotransmitter, exerts various
physiological functions including cardiac protection, angiogenesis, anti-inflammatory, and …