Targeted delivery to tumors: multidirectional strategies to improve treatment efficiency
OM Kutova, EL Guryev, EA Sokolova, R Alzeibak… - Cancers, 2019 - mdpi.com
Malignant tumors are characterized by structural and molecular peculiarities providing a
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …
Diagnostic and therapeutic approaches for glioblastoma and neuroblastoma cancers using chlorotoxin nanoparticles
Simple Summary Glioblastoma multiforme (GB) and neuroblastomas (NBs) are nervous
system cancers that are difficult to diagnosis and treat. Chlorotoxin (CTX), is a peptide …
system cancers that are difficult to diagnosis and treat. Chlorotoxin (CTX), is a peptide …
Diversity of potassium channel ligands: focus on scorpion toxins
AI Kuzmenkov, EV Grishin, AA Vassilevski - Biochemistry (Moscow), 2015 - Springer
Potassium (K+) channels are a widespread superfamily of integral membrane proteins that
mediate selective transport of K+ ions through the cell membrane. They have been found in …
mediate selective transport of K+ ions through the cell membrane. They have been found in …
Labelled animal toxins as selective molecular markers of ion channels: Applications in neurobiology and beyond
AI Kuzmenkov, AA Vassilevski - Neuroscience Letters, 2018 - Elsevier
Animal toxins are traditional and indispensible molecular tools that find application in
different fields of biochemistry, neurobiology and pharmacology. These compounds possess …
different fields of biochemistry, neurobiology and pharmacology. These compounds possess …
Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10. 1
L Moreels, S Peigneur, Y Yamaguchi, K Vriens… - Peptides, 2017 - Elsevier
Peptide toxins, such as scorpion peptides, are interesting lead compounds in the search for
novel drugs. In this paper, the focus is on the scorpion peptide κ-hefutoxin 1. This peptide …
novel drugs. In this paper, the focus is on the scorpion peptide κ-hefutoxin 1. This peptide …
[HTML][HTML] Venom peptides–A comprehensive translational perspective in pain management
V Vidya, RR Achar, MU Himathi, N Akshita… - Current Research in …, 2021 - Elsevier
Venom peptides have been evolving complex therapeutic interventions that potently and
selectively modulate a range of targets such as ion channels, receptors, and signaling …
selectively modulate a range of targets such as ion channels, receptors, and signaling …
Chemical synthesis and functional characterization of LaIT3, an insecticidal two-domain peptide in Liocheles australasiae venom
S Sakai, Y Fujita, H Juichi, Y Nakagawa, M Miyashita - Toxicon, 2024 - Elsevier
LaIT3, belonging to the β-KTx family, is an insecticidal peptide in the venom of the Liocheles
australasiae scorpion. Peptides in the family consist of two structural domains: an N-terminal …
australasiae scorpion. Peptides in the family consist of two structural domains: an N-terminal …
Trancriptomic approach reveals the molecular diversity of Hottentotta conspersus (Buthidae) venom
Scorpion venom consists of a complex mixture of molecules including biologically active
compounds. Because of their high potency and selectivity, toxins have medical applicability …
compounds. Because of their high potency and selectivity, toxins have medical applicability …
Surface-decoration strategies in nanomedicine for cancer treatment
Nanotechnology has gained major interest in cancer therapeutics mainly on account of the
imploring characteristic properties that nanoparticles exhibit. These include protection …
imploring characteristic properties that nanoparticles exhibit. These include protection …
[PDF][PDF] ANDROCTONUS CRASSİCAUDA AKREP ZEHRİNİN ANTİKANSER ÖZELLİĞİNİN İNCELENMESİ
M Tiken - 2022 - acikerisim.harran.edu.tr
Günümüzde çağımızın öldürücü hastalığı olan kansere karşı yapılan klasik tıbbi ilaç
tedavilerinde kalıcı ve iyileştirici sonuçlar alınamamaktadır. Ayrıca gücünü doğal ürünlerden …
tedavilerinde kalıcı ve iyileştirici sonuçlar alınamamaktadır. Ayrıca gücünü doğal ürünlerden …