The HIV-1 nucleocapsid protein (NC) is a nucleic acid chaperone, which remodels nucleic
acid structures so that the most thermodynamically stable conformations are formed. This …

One salient feature of reverse transcription in retroviruses, notably in the human
immunodeficiency virus type 1, is that it requires the homologous nucleocapsid (NC) protein …

HIV-1 nucleocapsid protein (NC) is a small basic protein generated by the cleavage of the
Gag structural polyprotein precusor by the viral protease during virus assembly in the …

Ensuring the correct folding of RNA molecules in the cell is of major importance for a large
variety of biological functions. Therefore, chaperone proteins that assist RNA in adopting …

HIV reverse transcription and nucleocapsid. After the capsid has entered the cell, reverse
transcriptase (A) creates a DNA copy (green) of the HIV RNA genome (yellow), using a …

The human immunodeficiency virus type 1 nucleocapsid protein (NCp7) plays an important
role in the second strand transfer during reverse transcription. It promotes annealing of the …

Fluorescent amino acids bearing environment-sensitive fluorophores are highly valuable
tools for site-selective probing of peptide/ligand interactions. Herein, we synthesized a …

In this work an improved stable isotope labeling protocol for nucleic acids is introduced. The
novel building blocks eliminate/minimize homonuclear 13C and 1H scalar couplings thus …

The nucleocapsid protein NCp7 of HIV-1 possesses nucleic acid chaperone properties that
are thought to be crucial throughout the viral life cycle. These properties promote the …

HIV-1 reverse transcription involves several nucleic acid rearrangements, which are
catalyzed by the nucleocapsid protein (NC). Annealing of the trans-activation response …