Effects of extracellular matrix viscoelasticity on cellular behaviour
Substantial research over the past two decades has established that extracellular matrix
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …
Advances in gelatin bioinks to optimize bioprinted cell functions
Gelatin is a widely utilized bioprinting biomaterial due to its cell‐adhesive and enzymatically
cleavable properties, which improve cell adhesion and growth. Gelatin is often covalently …
cleavable properties, which improve cell adhesion and growth. Gelatin is often covalently …
Bioprinted anisotropic scaffolds with fast stress relaxation bioink for engineering 3D skeletal muscle and repairing volumetric muscle loss
Viscoelastic hydrogels can enhance 3D cell migration and proliferation due to the faster
stress relaxation promoting the arrangement of the cellular microenvironment. However …
stress relaxation promoting the arrangement of the cellular microenvironment. However …
[HTML][HTML] Calponin 1 increases cancer-associated fibroblasts-mediated matrix stiffness to promote chemoresistance in gastric cancer
Y Lu, Z Jin, J Hou, X Wu, Z Yu, L Yao, T Pan, X Chang… - Matrix Biology, 2023 - Elsevier
The mechanical microenvironment regulated by cancer-associated fibroblasts (CAFs)
influence tumor progression. Chemotherapeutic interventions including 5-Fluorouracil (5-Fu) …
influence tumor progression. Chemotherapeutic interventions including 5-Fluorouracil (5-Fu) …
Cell cycle progression in confining microenvironments is regulated by a growth-responsive TRPV4-PI3K/Akt-p27Kip1 signaling axis
In tissues, cells reside in confining microenvironments, which may mechanically restrict the
ability of a cell to double in size as it prepares to divide. How confinement affects cell cycle …
ability of a cell to double in size as it prepares to divide. How confinement affects cell cycle …
Nanoindentation of soft biological materials
L Qian, H Zhao - Micromachines, 2018 - mdpi.com
Nanoindentation techniques, with high spatial resolution and force sensitivity, have recently
been moved into the center of the spotlight for measuring the mechanical properties of …
been moved into the center of the spotlight for measuring the mechanical properties of …
Distinguishing poroelasticity and viscoelasticity of brain tissue with time scale
L Su, M Wang, J Yin, F Ti, J Yang, C Ma, S Liu, TJ Lu - Acta Biomaterialia, 2023 - Elsevier
Brain tissue is considered to be biphasic, with approximately 80% liquid and 20% solid
matrix, thus exhibiting viscoelasticity due to rearrangement of the solid matrix and …
matrix, thus exhibiting viscoelasticity due to rearrangement of the solid matrix and …
Biomimetic tumor microenvironments based on collagen matrices
The extracellular matrix (ECM) establishes the basis for the cell's microenvironment
providing structural and mechanical support to cells and tissues, and regulating multiple cell …
providing structural and mechanical support to cells and tissues, and regulating multiple cell …
Quantifying the impact of cancer on the viscoelastic properties of the prostate gland using a quasi-linear viscoelastic model
Pathological disorders can alter the mechanical properties of biological tissues, and
studying such changes can help to better understand the disease progression. The prostate …
studying such changes can help to better understand the disease progression. The prostate …
Microscale characterisation of the time-dependent mechanical behaviour of brain white matter
A Jamal, A Bernardini, D Dini - Journal of the Mechanical Behavior of …, 2022 - Elsevier
Brain mechanics is a topic of deep interest because of the significant role of mechanical
cues in both brain function and form. Specifically, capturing the heterogeneous and …
cues in both brain function and form. Specifically, capturing the heterogeneous and …