[HTML][HTML] The quest for multiscale brain modeling
E D'Angelo, V Jirsa - Trends in neurosciences, 2022 - cell.com
Addressing the multiscale organization of the brain, which is fundamental to the dynamic
repertoire of the organ, remains challenging. In principle, it should be possible to model …
repertoire of the organ, remains challenging. In principle, it should be possible to model …
[HTML][HTML] Data-driven multiscale computational models of cortical and subcortical regions
S Ramaswamy - Current opinion in neurobiology, 2024 - Elsevier
Data-driven computational models of neurons, synapses, microcircuits, and mesocircuits
have become essential tools in modern brain research. The goal of these multiscale models …
have become essential tools in modern brain research. The goal of these multiscale models …
[HTML][HTML] Systematic integration of structural and functional data into multi-scale models of mouse primary visual cortex
Structural rules underlying functional properties of cortical circuits are poorly understood. To
explore these rules systematically, we integrated information from extensive literature …
explore these rules systematically, we integrated information from extensive literature …
The Neurodata Without Borders ecosystem for neurophysiological data science
The neurophysiology of cells and tissues are monitored electrophysiologically and optically
in diverse experiments and species, ranging from flies to humans. Understanding the brain …
in diverse experiments and species, ranging from flies to humans. Understanding the brain …
BrainPy, a flexible, integrative, efficient, and extensible framework for general-purpose brain dynamics programming
Elucidating the intricate neural mechanisms underlying brain functions requires integrative
brain dynamics modeling. To facilitate this process, it is crucial to develop a general-purpose …
brain dynamics modeling. To facilitate this process, it is crucial to develop a general-purpose …
Thalamic control of sensory processing and spindles in a biophysical somatosensory thalamoreticular circuit model of wakefulness and sleep
E Iavarone, J Simko, Y Shi, M Bertschy… - Cell Reports, 2023 - cell.com
Thalamoreticular circuitry plays a key role in arousal, attention, cognition, and sleep
spindles, and is linked to several brain disorders. A detailed computational model of mouse …
spindles, and is linked to several brain disorders. A detailed computational model of mouse …
Connectivity concepts in neuronal network modeling
J Senk, B Kriener, M Djurfeldt, N Voges… - PLoS computational …, 2022 - journals.plos.org
Sustainable research on computational models of neuronal networks requires published
models to be understandable, reproducible, and extendable. Missing details or ambiguities …
models to be understandable, reproducible, and extendable. Missing details or ambiguities …
Brain Modeling ToolKit: An open source software suite for multiscale modeling of brain circuits
Experimental studies in neuroscience are producing data at a rapidly increasing rate,
providing exciting opportunities and formidable challenges to existing theoretical and …
providing exciting opportunities and formidable challenges to existing theoretical and …
Model simulations unveil the structure-function-dynamics relationship of the cerebellar cortical microcircuit
R De Schepper, A Geminiani, S Masoli… - Communications …, 2022 - nature.com
The cerebellar network is renowned for its regular architecture that has inspired foundational
computational theories. However, the relationship between circuit structure, function and …
computational theories. However, the relationship between circuit structure, function and …
Data-driven multiscale model of macaque auditory thalamocortical circuits reproduces in vivo dynamics
We developed a detailed model of macaque auditory thalamocortical circuits, including
primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus …
primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus …