Structural engineering of polyurethanes for biomedical applications

H Wang, T Li, J Li, R Zhao, A Ding, FJ Xu - Progress in Polymer Science, 2024 - Elsevier
Polyurethane, a synthetic polymer distinguished by its urethane (carbamate,-NHCOO-)
and/or urea (-NHCONH-) linkages, has been applied in various industries since its discovery …

siRNA‐based nanotherapeutics as emerging modalities for immune‐mediated diseases: A preliminary review

S Sargazi, R Arshad, R Ghamari… - Cell Biology …, 2022 - Wiley Online Library
Immune‐mediated diseases (IMDs) are chronic conditions that have an immune‐mediated
etiology. Clinically, these diseases appear to be unrelated, but pathogenic pathways have …

Smart liposomal nanocarrier enhanced the treatment of ischemic stroke through neutrophil extracellular traps and cyclic guanosine monophosphate-adenosine …

S Sun, W Lv, S Li, Q Zhang, W He, Z Min, C Teng… - ACS …, 2023 - ACS Publications
Brain inflammation is regarded as one of the leading causes that aggravates secondary
brain injury and hinders the prognosis of ischemic stroke. After ischemic stroke, high …

Colon-Targeting Angelica sinensis Polysaccharide Nanoparticles with Dual Responsiveness for Alleviation of Ulcerative Colitis

Y Xu, BW Zhu, R Sun, X Li, D Wu… - ACS Applied Materials & …, 2023 - ACS Publications
Intestinal immune dysfunction and gut microbiota dysbiosis are critically causative factors in
the pathogenesis of ulcerative colitis (UC); however, the current first-line drugs for UC …

ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment

W Muhammad, J Zhu, Z Zhai, J Xie, J Zhou, X Feng… - Acta biomaterialia, 2022 - Elsevier
The acute lung injury (ALI) is an inflammatory disorder associated with cytokine storm, which
activates various reactive oxygen species (ROS) signaling pathways and causes severe …

Precise Regulation of Inflammation and Oxidative Stress by ROS‐Responsive Prodrug Coated Balloon for Preventing Vascular Restenosis

J Zhao, J Fu, F Jia, J Li, B Yu, Y Huang… - Advanced Functional …, 2023 - Wiley Online Library
Vascular restenosis after balloon dilation is largely caused by the over‐proliferation of
smooth muscle cells, which is triggered and exacerbated by local excessive inflammation …

NIR light‐facilitated bone tissue engineering

Q Feng, X Zhou, C He - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
In the last decades, near‐infrared (NIR) light has attracted considerable attention due to its
unique properties and numerous potential applications in bioimaging and disease …

In vivo self-assembled shape-memory polyurethane for minimally invasive delivery and therapy

S Li, H Zhang, J Xie, Z Wang, K Wang, Z Zhai… - Materials …, 2023 - pubs.rsc.org
Advanced elastomers are highly in demand for the fabrication of medical devices for
minimally invasive surgery (MIS). Herein, a shape memory and self-healing polyurethane …

Reactive oxygen species-responsive polymer drug delivery systems

J Liu, B Jia, Z Li, W Li - Frontiers in Bioengineering and Biotechnology, 2023 - frontiersin.org
Applying reactive polymer materials sensitive to biological stimuli has recently attracted
extensive research interest. The special physiological effects of reactive oxygen species …

Recent advances and prospects in nanomaterials for bacterial sepsis management

Y Liu, Y Li, C Zhou, L Shi - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Bacterial sepsis is a life-threatening condition caused by bacteria entering the bloodstream
and triggering an immune response, underscoring the importance of early recognition and …