Flavonoids: promising anticancer agents

W Ren, Z Qiao, H Wang, L Zhu… - Medicinal research …, 2003 - Wiley Online Library
Flavonoids are polyphenolic compounds that are ubiquitously in plants. They have been
shown to possess a variety of biological activities at nontoxic concentrations in organisms …

[HTML][HTML] Flavonoids: A versatile source of anticancer drugs

MK Chahar, N Sharma, MP Dobhal… - Pharmacognosy …, 2011 - ncbi.nlm.nih.gov
An exponential increase in the number of studies investigating how different components of
the diet interact at the molecular and cellular level to determine the fate of a cell has been …

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

YJ Moon, X Wang, ME Morris - Toxicology in vitro, 2006 - Elsevier
Flavonoids are present in fruits, vegetables and beverages derived from plants (tea, red
wine), and in many dietary supplements or herbal remedies including Ginkgo Biloba, Soy …

Cancer chemoprevention through dietary flavonoids: what's limiting?

H Amawi, CR Ashby, AK Tiwari - Chinese journal of cancer, 2017 - Springer
Flavonoids are polyphenols that are found in numerous edible plant species. Data obtained
from preclinical and clinical studies suggest that specific flavonoids are chemo-preventive …

Biochanin A: A novel bioactive multifunctional compound from nature

A Sarfraz, M Javeed, MA Shah, G Hussain… - Science of the Total …, 2020 - Elsevier
Natural products (NPs) will continue to serve humans as matchless source of novel drug
leads and an inspiration for the synthesis of non-natural drugs. As our scientific …

Phyto-oestrogens, their mechanism of action: current evidence for a role in breast and prostate cancer

PJ Magee, IR Rowland - British Journal of Nutrition, 2004 - cambridge.org
The incidence of hormone-dependent cancers, such as those of the breast and prostate, is
much lower in Eastern countries such as China and Japan in comparison with the Western …

Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy?

V Beck, U Rohr, A Jungbauer - The Journal of steroid biochemistry and …, 2005 - Elsevier
The benefits of plant extracts from soy and red clover as alternatives to conventional
hormone replacement therapy (HRT) have been debated in the past. Here, an attempt has …

Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME

Z Yang, K Kulkarni, W Zhu, M Hu - Anti-Cancer Agents in …, 2012 - ingentaconnect.com
Genistein, one of the most active natural flavonoids, exerts various biological effects
including chemoprevention, antioxidation, antiproliferation and anticancer. More than 30 …

Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate …

X Zi, R Agarwal - Proceedings of the National Academy of …, 1999 - National Acad Sciences
Reduction in serum prostate-specific antigen (PSA) levels has been proposed as an
endpoint biomarker for hormone-refractory human prostate cancer intervention. We …

Anticancer therapeutic potential of soy isoflavone, genistein

MH Ravindranath, S Muthugounder, N Presser… - Complementary and …, 2004 - Springer
Abstract Genistein (4′ 5, 7-trihydroxyisoflavone) occurs as a glycoside (genistin) in the
plant family Leguminosae, which includes the soybean (Glycine max). A significant …