Fetal–neonatal exposure to antibiotics and NEC development: a systematic review and meta-analysis

DH Klerk, LK van Avezaath, EAH Loeffen… - Frontiers in …, 2023 - frontiersin.org
Background Fetal and neonatal exposure to antibiotics may contribute to the development of
necrotizing enterocolitis (NEC) in preterm infants. This systematic review and meta-analysis …

Pathogenesis of necrotising enterocolitis: The impact of the altered gut microbiota and antibiotic exposure in preterm infants

AA Raba, A O'Sullivan, J Miletin - Acta Paediatrica, 2021 - Wiley Online Library
Necrotising enterocolitis (NEC) is a devastating condition with high morbidity and mortality
seen predominately in preterm infants. Multiple factors are associated with the pathogenesis …

The NICU Antibiotics and Outcomes (NANO) trial: a randomized multicenter clinical trial assessing empiric antibiotics and clinical outcomes in newborn preterm infants

MJ Morowitz, AC Katheria, RA Polin, E Pace… - Trials, 2022 - Springer
Background Early-onset sepsis is an important cause of neonatal morbidity and mortality in
the preterm population. Infants perceived to be at increased risk for early-onset sepsis are …

[HTML][HTML] Interventions to reduce preterm birth and stillbirth, and improve outcomes for babies born preterm in low-and middle-income countries: a systematic review

E Wastnedge, D Waters, SR Murray… - Journal of Global …, 2021 - ncbi.nlm.nih.gov
Background Reducing preterm birth and stillbirth and improving outcomes for babies born
too soon is essential to reduce under-5 mortality globally. In the context of a rapidly evolving …

Association of initial empirical antibiotic therapy with increased risk of necrotizing enterocolitis

P Rina, Y Zeng, J Ying, Y Qu, D Mu - European journal of pediatrics, 2020 - Springer
Whether the prophylactic use of antibiotics increase the risk of necrotizing enterocolitis
(NEC) remains controversial. This review aims to investigate initial empirical antibiotic …

The impact of maternal antibiotics on neonatal disease

BD Reed, KR Schibler, H Deshmukh… - The Journal of …, 2018 - Elsevier
Objectives We examined the impact of prenatal exposure to maternal antibiotics on risk of
necrotizing enterocolitis (NEC), late onset sepsis (LOS), and death in infants born preterm …

Audit of antibiotic prescribing practices for neonatal sepsis and measurement of outcome in new born unit at Kenyatta National Hospital

PJ Tank, A Omar, R Musoke - International Journal of …, 2019 - Wiley Online Library
Background. Neonatal sepsis is a leading cause of morbidity and mortality globally. A high
index of suspicion is required since features of sepsis are nonspecific. Auditing of antibiotic …

Neonatal methicillin-resistant Staphylococcus aureus colonization and infection

Y Shirai, H Arai, K Tamaki, H Konishi… - Journal of Neonatal …, 2017 - content.iospress.com
METHODS: We conducted retrospective analysis of 1716 neonates hospitalized in our
perinatal care center. RESULTS: 120 cases had MRSA colonization (6.99%) and among …

[PDF][PDF] Duration of empirical therapy in neonatal bacterial meningitis with third generation cephalosporin: a multicenter retrospective study

Z Zhao, X Hua, J Yu, H Zhang, J Li, Z Li - Archives of Medical Science, 2019 - termedia.pl
Results Neonates were identified as having bacterial meningitis based on the results of CSF
culture tests of all suspected cases. According to the GOS, neonates were divided into two …

Incidence of late-onset sepsis in very low birth weight and extremely low birth weight infants and risk factors for late-onset sepsis

XP Zhao, W Zhou, XF Li, YY Song… - … Dang dai er ke za zhi …, 2017 - europepmc.org
Objective To investigate the incidence of late-onset sepsis (LOS) in very low birth weight
(VLBW) and extremely low birth weight (ELBW) infants in the neonatal intensive care unit …