Intense exercise has unique effects on both insulin release and its roles in glucoregulation: implications for diabetes

EB Marliss, M Vranic - Diabetes, 2002 - Am Diabetes Assoc
In intense exercise (> 80% V o2max), unlike at lesser intensities, glucose is the exclusive
muscle fuel. It must be mobilized from muscle and liver glycogen in both the fed and fasted …

Exercise and the regulation of hepatic metabolism

E Trefts, AS Williams, DH Wasserman - Progress in molecular biology and …, 2015 - Elsevier
The accelerated metabolic demands of the working muscle cannot be met without a robust
response from the liver. If not for the hepatic response, sustained exercise would be …

[HTML][HTML] The role of the autonomic nervous liver innervation in the control of energy metabolism

CX Yi, SE La Fleur, E Fliers, A Kalsbeek - Biochimica et Biophysica Acta …, 2010 - Elsevier
Despite a longstanding research interest ever since the early work by Claude Bernard, the
functional significance of autonomic liver innervation, either sympathetic or parasympathetic …

The physiological regulation of glucose flux into muscle in vivo

DH Wasserman, L Kang, JE Ayala… - Journal of …, 2011 - journals.biologists.com
Skeletal muscle glucose uptake increases dramatically in response to physical exercise.
Moreover, skeletal muscle comprises the vast majority of insulin-sensitive tissue and is a site …

Splanchnic regulation of glucose production

J Wahren, K Ekberg - Annu. Rev. Nutr., 2007 - annualreviews.org
The liver plays a key role for the maintenance of blood glucose homeostasis under widely
changing physiological conditions. In the overnight fasted state, breakdown of hepatic …

Effects of physical activity upon the liver

RJ Shephard, N Johnson - European journal of applied physiology, 2015 - Springer
Purpose To review the responses of the liver to acute and chronic physical activity and to
summarize relationships between physical activity and liver health. Methods A systematic …

[HTML][HTML] Maternal rumen-protected methionine supplementation and its effect on blood and liver biomarkers of energy metabolism, inflammation, and oxidative stress …

CB Jacometo, Z Zhou, D Luchini, E Trevisi… - Journal of dairy …, 2016 - Elsevier
In nonruminants, nutrition during pregnancy can program offspring development,
metabolism, and health in later life. Rumen-protected Met (RPM) supplementation during the …

Control of hepatocyte metabolism by sympathetic and parasympathetic hepatic nerves

GP Püschel - The Anatomical Record Part A: Discoveries in …, 2004 - Wiley Online Library
More than any other organ, the liver contributes to maintaining metabolic equilibrium of the
body, most importantly of glucose homeostasis. It can store or release large quantities of …

Glucoregulation during exercise: the role of the neuroendocrine system

RH Coker, M Kjaer - Sports Medicine, 2005 - Springer
Under normal healthy conditions, exercise initiates simultaneous elevations in hepatic
glucose production (glucose R a) and glucose utilisation. As a result, circulating glucose …

Hepatokines—a novel group of exercise factors

C Weigert, M Hoene, P Plomgaard - Pflügers Archiv-European Journal of …, 2019 - Springer
Regular physical activity not only improves the exercise capacity of the skeletal muscle
performing the contractions, but it is beneficial for the whole body. An extensive search for …