Atherosclerotic renovascular disease (RVD) reduces renal blood flow (RBF) and GFR and
accelerates poststenotic kidney (STK) tissue injury. Preclinical studies indicate that …

Chronic kidney disease (CKD) affects 1 in 10 members of the general population, placing
these patients at an increasingly high risk of kidney failure. Despite the significant burden of …

Renal artery stenosis (RAS) elicits the development of hypertension and post-stenotic
kidney damage, which may become irresponsive to restoration of arterial patency. Rather …

Tumor necrosis factor (TNF)-α-induced gene/protein (TSG)-6 regulates the
immunomodulatory properties of mesenchymal stem cells (MSCs), but its ability to protect …

Genistein is a bioflavonoid mainly found in soybean. This study evaluated the effect of
genistein on vascular dysfunction and kidney damage in two-kidney, one-clipped (2K1C) …

Background. Chronic renal artery stenosis is considered one of the most common causes of
renovascular hypertension (RH). Chronic hypoxia can lead to irreversible damage to renal …

Atherosclerotic renal artery stenosis (ARAS) is associated with irreversible parenchymal
renal disease and regenerative stem cell therapies may improve renal outcomes. Hypoxia …

Renal artery stenosis (RAS) causes severe renovascular hypertension, worsening kidney
function, and increased cardiovascular morbidity. According to recent studies, mesenchymal …

Bone marrow mesenchymal stromal cell (MSC) is a potential alternative in regenerative
medicine and has great potential in many pathologic conditions including kidney disease …

Background: Mesenchymal stem cells (MSC) improve renal function and renovascular
hypertension in the 2-kidney 1-clip model (2K-1C). While MSC play an immunomodulatory …