Antibiotics-free nanomaterials against bacterial keratitis: Eliminating infections with reactive oxygen species (ROS)

L Zhou, Y Deng, Y Ren, HL Poon, WY Chu… - Chemical Engineering …, 2024 - Elsevier
Bacterial keratitis (BK), which accounts for over 50% of the reported cases of microbial
keratitis, is a condition that can result in vision loss and blindness if left untreated. Antibiotics …

Effective removal of Rose Bengal using Ni-Co-Zn layered triple hydroxide: Studies on batch adsorption, mechanism, selectivity, co-ions, and reusability

G Sriram, S Thangarasu, K Selvakumar… - Colloids and Surfaces A …, 2024 - Elsevier
The simple co-precipitation approach was used to produce Ni-Co-Zn layered triple
hydroxide (NCZ), and its batch adsorption removal of Rose Bengal (RB) was investigated …

[HTML][HTML] Managing Corneal Infections: Out with the old, in with the new?

S Marasini, JP Craig, SJ Dean, LG Leanse - Antibiotics, 2023 - mdpi.com
There have been multiple reports of eye infections caused by antibiotic-resistant bacteria,
with increasing evidence of ineffective treatment outcomes from existing therapies. With …

Steroids in the management of infectious keratitis

JD Keenan - Cornea, 2023 - journals.lww.com
Purpose: To summarize the evidence base on the use of topical corticosteroids for infectious
keratitis. Methods: Narrative review. Results: Infectious keratitis is a painful condition that …

Clinical features and treatment outcomes of carbapenem-resistant Pseudomonas aeruginosa keratitis

FE Tribin, C Lieux, J Maestre-Mesa… - JAMA …, 2024 - jamanetwork.com
Importance Evaluation of the microbiological diagnostic profile of multidrug-
resistantPseudomonas aeruginosakeratitis and potential management with rose bengal …

[HTML][HTML] Human corneal epithelial cell and fibroblast migration and growth factor secretion after rose bengal photodynamic therapy (RB-PDT) and the effect of …

N Chai, T Stachon, T Berger, Z Li, B Seitz… - Plos one, 2023 - journals.plos.org
Purpose To investigate human corneal epithelial cell and fibroblast migration and growth
factor secretion after rose bengal photodynamic therapy (RB-PDT) and the effect of …

[HTML][HTML] High-fluence accelerated PACK-CXL for bacterial keratitis using riboflavin/UV-A or rose Bengal/green in the ex vivo porcine cornea

NJ Lu, H Koliwer-Brandl, M Hillen… - … Vision Science & …, 2023 - iovs.arvojournals.org
Purpose: To investigate and compare the efficacy of high-fluence accelerated
photoactivated chromophore for keratitis–corneal cross-linking (PACK-CXL) using either …

Variations in irradiation energy and rose bengal concentration for photodynamic antimicrobial therapy of fungal keratitis isolates

A Arboleda, H Durkee, D Miller, MC Aguilar… - Lasers in Medical …, 2024 - Springer
The purpose is to assess the efficacy of rose bengal photodynamic antimicrobial therapy
(PDAT) using different irradiation energy levels and photosensitizer concentrations for the …

Rose Bengal Photodynamic Therapy (RB-PDT) Modulates the Inflammatory Response in LPS-Stimulated Human Corneal Fibroblasts By Influencing NF-κB and p38 …

N Chai, T Stachon, T Berger, Z Li, M Amini… - Current Eye …, 2024 - Taylor & Francis
Purpose To investigate the effect of rose bengal photodynamic therapy on
lipopolysaccharide-induced inflammation in human corneal fibroblasts. Furthermore, to …

Diagnosis and treatment of Acanthamoeba Keratitis: A scoping review demonstrating unfavorable outcomes

MLC Büchele, BF Nunes, FB Filippin-Monteiro… - Contact Lens and …, 2023 - Elsevier
Acanthamoeba spp. are pathogens that cause Acanthamoeba keratitis (AK), a serious
cornea inflammation that can lead to gradual loss of vision, permanent blindness, and …