Laboratory and clinical aspects of human herpesvirus 6 infections

H Agut, P Bonnafous… - Clinical microbiology …, 2015 - Am Soc Microbiol
SUMMARY Human herpesvirus 6 (HHV-6) is a widespread betaherpesvirus which is
genetically related to human cytomegalovirus (HCMV) and now encompasses two different …

Virus-mediated cell-cell fusion

H Leroy, M Han, M Woottum, L Bracq… - International Journal of …, 2020 - mdpi.com
Cell-cell fusion between eukaryotic cells is a general process involved in many
physiological and pathological conditions, including infections by bacteria, parasites, and …

An unbiased screen for human cytomegalovirus identifies neuropilin-2 as a central viral receptor

N Martinez-Martin, J Marcandalli, CS Huang, CP Arthur… - Cell, 2018 - cell.com
Characterizing cell surface receptors mediating viral infection is critical for understanding
viral tropism and developing antiviral therapies. Nevertheless, due to challenges associated …

Virus entry by endocytosis

J Mercer, M Schelhaas… - Annual review of …, 2010 - annualreviews.org
Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …

Classification of HHV-6A and HHV-6B as distinct viruses

D Ablashi, H Agut, R Alvarez-Lafuente, DA Clark… - Archives of …, 2014 - Springer
Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A
and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses …

CD46 is a cellular receptor for group B adenoviruses

A Gaggar, DM Shayakhmetov, A Lieber - Nature medicine, 2003 - nature.com
Group B adenoviruses, a subgenus of human Adenoviridae, are associated with a variety of
often-fatal illnesses in immunocompromised individuals, including bone marrow transplant …

[HTML][HTML] Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry

D Shukla, PG Spear - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
Glycosaminoglycan chains on cell surface proteoglycans provide initial docking sites for the
binding to eukaryotic cells of various viruses and other microorganisms. The ubiquitously …

Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism

D Wang, T Shenk - Proceedings of the National Academy of …, 2005 - National Acad Sciences
Human cytomegalovirus replicates in many different cell types, including epithelial cells,
endothelial cells, and fibroblasts. However, laboratory strains of the virus, many of which …

Update on human herpesvirus 6 biology, clinical features, and therapy

L De Bolle, L Naesens, E De Clercq - Clinical microbiology …, 2005 - Am Soc Microbiol
SUMMARY Human herpesvirus 6 (HHV-6) is a betaherpesvirus that is closely related to
human cytomegalovirus. It was discovered in 1986, and HHV-6 literature has expanded …

Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype

C Kemper, AC Chan, JM Green, KA Brett, KM Murphy… - Nature, 2003 - nature.com
The immune system must distinguish not only between self and non-self, but also between
innocuous and pathological foreign antigens to prevent unnecessary or self-destructive …