The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

[HTML][HTML] Mycobacterium Biofilms

J Esteban, M García-Coca - Frontiers in microbiology, 2018 - frontiersin.org
The genus Mycobacterium includes human pathogens (Mycobacterium tuberculosis and
Mycobacterium leprae) and environmental organisms known as non-tuberculous …

[HTML][HTML] Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection

JA Nick, RM Dedrick, AL Gray, EK Vladar, BE Smith… - Cell, 2022 - cell.com
Two mycobacteriophages were administered intravenously to a male with treatment-
refractory Mycobacterium abscessus pulmonary infection and severe cystic fibrosis lung …

[HTML][HTML] Diagnosis and treatment of nontuberculous mycobacterial lung disease: clinicians' perspectives

YJ Ryu, WJ Koh, CL Daley - Tuberculosis and respiratory …, 2016 - synapse.koreamed.org
Nontuberculous mycobacteria (NTM) are emerging pathogens that affect both
immunocompromised and immunocompetent patients. The incidence and prevalence of …

[HTML][HTML] Mechanopathology of biofilm-like Mycobacterium tuberculosis cords

R Mishra, M Hannebelle, VP Patil, A Dubois… - Cell, 2023 - cell.com
Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like
cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in …

[HTML][HTML] Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients

G Degiacomi, JC Sammartino, LR Chiarelli… - International journal of …, 2019 - mdpi.com
Nontuberculous mycobacteria (NTM) have recently emerged as important pathogens among
cystic fibrosis (CF) patients worldwide. Mycobacterium abscessus is becoming the most …

[HTML][HTML] Amikacin liposome inhalation suspension (ALIS) penetrates non-tuberculous mycobacterial biofilms and enhances amikacin uptake into macrophages

J Zhang, F Leifer, S Rose, DY Chun, J Thaisz… - Frontiers in …, 2018 - frontiersin.org
Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural
lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of …

Opportunistic pathogens in cystic fibrosis: epidemiology and pathogenesis of lung infection

AC Blanchard, VJ Waters - Journal of the Pediatric Infectious …, 2022 - academic.oup.com
Cystic fibrosis (CF) is one of the most common life-shortening genetic diseases in
Caucasians. Due to abnormal accumulation of mucus, respiratory failure caused by chronic …

[HTML][HTML] The extracellular matrix of mycobacterial biofilms: could we shorten the treatment of mycobacterial infections?

P Chakraborty, A Kumar - Microbial cell, 2019 - ncbi.nlm.nih.gov
A number of non-tuberculous mycobacterium species are opportunistic pathogens and
ubiquitously form biofilms. These infections are often recalcitrant to treatment and require …

[HTML][HTML] Bacterial biofilms in the human body: Prevalence and impacts on health and disease

EK Perry, MW Tan - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Bacterial biofilms can be found in most environments on our planet, and the human body is
no exception. Consisting of microbial cells encased in a matrix of extracellular polymers …