In recent years, advances in drug therapy for head and neck squamous cell carcinoma
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …

In recent years, with the advancement of next-generation sequencing (NGS) technology,
gene panel tests have been approved in the field of cancer diseases, and approaches to …

Poroma is a benign skin tumor exhibiting terminal sweat gland duct differentiation. The
present study aimed to explore the potential role of gene fusions in the tumorigenesis of …

IMPORTANCE Precision oncology using comprehensive genomic profiling (CGP) by next-
generation sequencing is aimed at companion diagnosis and genomic profiling. The clinical …

Although comprehensive genomic profiling has become standard in oncology for advanced
solid tumors, the full potential of circulating tumor DNA (ctDNA)-based profiling in capturing …

Simple Summary Neuroendocrine neoplasms are divided into two groups: well-
differentiated neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas …

Background To promote precision oncology in clinical practice, the Japanese Society of
Medical Oncology, the Japanese Society of Clinical Oncology, and the Japanese Cancer …

Approximately 1 in 2 Japanese people are estimated to be diagnosed with cancer during
their lifetime. Cancer still remains the leading cause of death in Japan, therefore the …

Background Implementation of personalized medicine requires the accessibility of tumor
molecular profiling in order to allow prioritization of appropriate targeted therapies for …

Previous clinical trials indicate that 10%–25% of patients received genomically matched
therapy after comprehensive genomic profiling (CGP) tests. However, the clinical utility of …