[HTML][HTML] Classical and reactive molecular dynamics: Principles and applications in combustion and energy systems

Q Mao, M Feng, XZ Jiang, Y Ren, KH Luo… - Progress in Energy and …, 2023 - Elsevier
Molecular dynamics (MD) has evolved into a ubiquitous, versatile and powerful
computational method for fundamental research in science branches such as biology …

An empirical polarizable force field based on the classical drude oscillator model: development history and recent applications

JA Lemkul, J Huang, B Roux, AD MacKerell Jr - Chemical reviews, 2016 - ACS Publications
Molecular mechanics force fields that explicitly account for induced polarization represent
the next generation of physical models for molecular dynamics simulations. Several …

PhysNet: A neural network for predicting energies, forces, dipole moments, and partial charges

OT Unke, M Meuwly - Journal of chemical theory and computation, 2019 - ACS Publications
In recent years, machine learning (ML) methods have become increasingly popular in
computational chemistry. After being trained on appropriate ab initio reference data, these …

CHARMM-GUI input generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM simulations using the CHARMM36 additive force field

J Lee, X Cheng, S Jo, AD MacKerell, JB Klauda, W Im - Biophysical journal, 2016 - cell.com
Proper treatment of nonbonded interactions is essential for the accuracy of molecular
dynamics (MD) simulations, especially in studies of lipid mono-and bilayers. The use of the …

Developing a fully glycosylated full-length SARS-CoV-2 spike protein model in a viral membrane

H Woo, SJ Park, YK Choi, T Park… - The journal of …, 2020 - ACS Publications
This technical study describes all-atom modeling and simulation of a fully glycosylated full-
length SARS-CoV-2 spike (S) protein in a viral membrane. First, starting from PDB: 6VSB …

Improving protein-ligand docking results with high-throughput molecular dynamics simulations

H Guterres, W Im - Journal of chemical information and modeling, 2020 - ACS Publications
Structure-based virtual screening relies on classical scoring functions that often fail to
reliably discriminate binders from nonbinders. In this work, we present a high-throughput …

CHARMM‐GUI Membrane Builder toward realistic biological membrane simulations

EL Wu, X Cheng, S Jo, H Rui, KC Song… - 2014 - Wiley Online Library
CHARMM‐GUI Membrane Builder, http://www. charmm‐gui. org/input/membrane, is a web‐
based user interface designed to interactively build all‐atom protein/membrane or …

CHARMM-GUI nanomaterial modeler for modeling and simulation of nanomaterial systems

YK Choi, NR Kern, S Kim, K Kanhaiya… - Journal of chemical …, 2021 - ACS Publications
Molecular modeling and simulation are invaluable tools for nanoscience that predict
mechanical, physicochemical, and thermodynamic properties of nanomaterials and provide …

CHARMM-GUI Glycan Modeler for modeling and simulation of carbohydrates and glycoconjugates

SJ Park, J Lee, Y Qi, NR Kern, HS Lee, S Jo… - …, 2019 - academic.oup.com
Characterizing glycans and glycoconjugates in the context of three-dimensional structures is
important in understanding their biological roles and developing efficient therapeutic agents …

Modeling molecular interactions in water: From pairwise to many-body potential energy functions

GA Cisneros, KT Wikfeldt, L Ojamäe, J Lu… - Chemical …, 2016 - ACS Publications
Almost 50 years have passed from the first computer simulations of water, and a large
number of molecular models have been proposed since then to elucidate the unique …