Candida albicans cell-type switching and functional plasticity in the mammalian host

SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …

Growth of Candida albicans hyphae

PE Sudbery - Nature Reviews Microbiology, 2011 - nature.com
The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …

Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

JR Naglik, SJ Challacombe, B Hube - Microbiology and molecular …, 2003 - Am Soc Microbiol
Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Candida albicans Cell Wall Proteins

WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Transcriptional Response of Candida albicans upon Internalization by Macrophages

MC Lorenz, JA Bender, GR Fink - Eukaryotic cell, 2004 - Am Soc Microbiol
The opportunistic fungal pathogen Candida albicans is both a benign gut commensal and a
frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate …

Candida albicans: A molecular revolution built on lessons from budding yeast

J Berman, PE Sudbery - Nature Reviews Genetics, 2002 - nature.com
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …

Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

AJP Brown, GD Brown, MG Netea, NAR Gow - Trends in microbiology, 2014 - cell.com
Metabolism is integral to the pathogenicity of Candida albicans, a major fungal pathogen of
humans. As well as providing the platform for nutrient assimilation and growth in diverse …

Tyrosol is a quorum-sensing molecule in Candida albicans

H Chen, M Fujita, Q Feng, J Clardy… - Proceedings of the …, 2004 - National Acad Sciences
The human fungal pathogen Candida albicans shows a significant lag in growth when
diluted into fresh minimal medium. This lag is abolished by the addition of conditioned …

A Pseudomonas aeruginosa quorum‐sensing molecule influences Candida albicans morphology

DA Hogan, Å Vik, R Kolter - Molecular microbiology, 2004 - Wiley Online Library
Candida albicans is an opportunistic pathogen that is commonly found as a member of the
human microflora. The ability of C. albicans to alter its cellular morphology has been …