Effective drug therapy to optimally influence disease requires an understanding of a drug's
pharmacokinetic, pharmacodynamic, and pharmacogenomic interrelationships. In …

Propofol is an intravenous agent used commonly for the induction and maintenance of
anesthesia, procedural, and critical care sedation in children. The mechanisms of action on …

Information on drug absorption and disposition in infants and children has increased
considerably over the past 2 decades. However, the impact of specific age-related effects on …

Children differ from adults in many aspects of pharmacotherapy, including capabilities for
drug administration, medicine-related toxicity, and taste preferences. It is essential that …

A number of anatomical and physiological factors determine the pharmacokinetic profile of a
drug. Differences in physiology in paediatric populations compared with adults can influence …

Many physiologic differences between children and adults may result in age-related
changes in pharmacokinetics and pharmacodynamics. Factors such as gastric pH and …

Importance Despite concerns about rising treatment of young people with antipsychotic
medications, little is known about trends and patterns of their use in the United States …

Adequate nutrition during cancer plays a decisive role in several clinical outcome measures,
such as treatment response, quality of life, and cost of care. However, the importance of …

Despite much progress in regulations to improve paediatric drug development, there
remains a significant need to develop better medications for children. For the design of oral …

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLYWorking in the
laboratory or office, you use a diverse assortment of basic information to design, conduct …