New mechanism for cinchona alkaloid-catalysis allows for an efficient thiophosphorylation reaction

N Salehi Marzijarani, Y Lam, X Wang… - Journal of the …, 2020 - ACS Publications
An efficient synthesis of nucleoside 5′-monothiophosphates under mild reaction conditions
using commercially available thiophosphoryl chloride was achieved with a cinchona …

Reactions of Aldehydes and Ketones and their Derivatives

BA Murray - Organic Reaction Mechanisms 2011: An annual …, 2014 - Wiley Online Library
Carbohydrate‐based benzylidene acetals undergo reductive ring opening. 1‐β‐O‐Acyl
glucoside conjugates of phenylacetic acids have been synthesized, and their acyl migration …

Reactivity of Indolylmethylacetates with N, O, and S Soft Nucleophiles: Evidence of 2‐Alkylideneindolenines and 3‐Alkylideneindoleninium Generation by ESI‐MS …

A Arcadi, G Berden, A Ciogli, D Corinti… - European Journal of …, 2022 - Wiley Online Library
Abstract The synthesis of (aminomethyl),(tosylmethyl), and (aryloxymethyl) indoles starting
from indolylmethylacetates and N, O, and S soft nucleophiles has been developed. ESI‐MS …

Asymmetric Organocatalyzed Aza‐Henry Reaction of Hydrazones: Experimental and Computational Studies

IG Sonsona, JV Alegre‐Requena… - … A European Journal, 2020 - Wiley Online Library
The first asymmetric catalyzed aza‐Henry reaction of hydrazones is presented. In this
process, quinine was used as the catalyst to synthesize different alkyl substituted β …

Hydrogen‐Bond‐Induced Chiral Axis Construction: Theoretical Study of Cinchonine–Thiourea‐Catalyzed Enantioselective Intramolecular Cycloaddition

C Shan, T Zhang, Q Xiong, H Yan… - Chemistry–An Asian …, 2019 - Wiley Online Library
Theoretical calculations were performed to investigate the mechanism and enantioselectivity
of cinchonine–thiourea‐catalyzed intramolecular hetero‐Diels–Alder cycloaddition of …

Photophysics of perylene monoimide-labelled organocatalysts

D Zheng, MR Oskouei, HJ Sanders, J Qian… - Photochemical & …, 2019 - Springer
We designed and synthesized cinchona alkaloid derivates PMI-BnCPD, 1 and PMI-dHQD, 2,
in which a fluorescent perylene monoimide unit is linked to the quinuclidine fragment. The …

Primary Amine Catalyzed Activation of Carbonyl Compounds: A Study on Reaction Pathways and Reactive Intermediates by Mass Spectrometry

A Iazzetti, G Mazzoccanti, G Bencivenni… - European Journal of …, 2022 - Wiley Online Library
The field of organocatalysis is expanding at a fast pace. Its growth is sustained by major
stimuli, such as the effort toward an understanding of the mechanisms of reaction and …

Unraveling the Origin of Solvent Induced Enantioselectivity in the Henry Reaction with Cinchona Thiourea as Catalyst

M Heshmat - The Journal of Physical Chemistry A, 2018 - ACS Publications
In this work, we report an energy decomposition and electronic structure analysis using DFT
calculations for the C–C coupling step in the Henry reaction with cinchona thiourea as …

Synthesis and catalytic application of two mononuclear complexes bearing diethylenetriamine derivative ligand

C Liu, Z Yang, H Guo, YC Zhao - Molecules, 2020 - mdpi.com
Two mononuclear zero-dimensional Ni (II) and Zn (II) complexes bearing diethylenetriamine
derivative ligand, namely [NiL (CH3COO) 2 (H2O)](1) and [ZnL (CH3COO) 2](2)[L= N, N'-bis …

Henry reaction catalyzed by recyclable polyamine

B Lv, Q Feng, P Cai, G Chen, X Bao - Tetrahedron Letters, 2023 - Elsevier
The catalytic Henry reaction is an important Csingle bondC bond forming reaction between
aldehyde/ketone and nitroalkane. Herein, a metal-free recyclable polyamine JP-2Y was …