Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Fluorescent small molecules are powerful tools for visualizing biological events, embodying
an essential facet of chemical biology. Since the discovery of the first organic fluorophore …

Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

Unlike amyloid aggregates, amorphous protein aggregates with no defined structures have
been challenging to target and detect in a complex cellular milieu. In this study, we rationally …

Intracellular pH plays an important role in many biological and pathological processes.
Small‐molecule based pH probes are found to be the most effective for pH sensing because …

Nitrogen-containing heterocycles are ubiquitous in natural products and drugs. Various
organic small molecules with nitrogen-containing heterocycles, such as nitrogen-containing …

Herein, a class of novel photoswitchable tristate fluorescent polymeric nanoparticles (TS‐
PFPNs) consisting of a well‐designed perylenediimide‐spiropyran conjugate (PDI‐SP), two …

Fluorescent probes have gained profound use in biotechnology, drug discovery, medical
diagnostics, molecular and cell biology. The development of methods for the translation of …

The current theoretical work analyzes the optimal structure and vibrational assignments of 2-
[[1-(cyclopropyl methox)-4-hydroxy-2-oxoquinoline-3-carbonyl] amino] acetic acid (2C2O) …

Copper is one of the most important transition metals in our body for various physiological
functions. An imbalance in the homeostasis of copper in our body can lead to various …