Acute graft-versus-host disease

F Malard, E Holler, BM Sandmaier, H Huang… - Nature Reviews …, 2023 - nature.com
Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

[HTML][HTML] Chronic graft-versus-host disease

SJ Lee, G Vogelsang, MED Flowers - Biology of Blood and Marrow …, 2003 - Elsevier
Chronic graft-versus-host disease (GVHD) remains a vexing and dangerous complication of
allogeneic stem cell transplantation. Mild forms of chronic GVHD are often manageable with …

Risk factors for acute GVHD and survival after hematopoietic cell transplantation

M Jagasia, M Arora, MED Flowers… - Blood, The Journal …, 2012 - ashpublications.org
Risk factors for acute GVHD (AGVHD), overall survival, and transplant-related mortality were
evaluated in adults receiving allogeneic hematopoietic cell transplants (1999-2005) from …

Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a …

J Finke, WA Bethge, C Schmoor, HD Ottinger… - The lancet …, 2009 - thelancet.com
Background Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality
after allogeneic haematopoietic cell transplantation from unrelated donors. Anti-T-cell …

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

BJ Druker, NB Lydon - The Journal of clinical investigation, 2000 - Am Soc Clin Investig
AProtein kinase targeted. A number of these molecules are broad-spectrum kinase
inhibitors. BStaurosporine class represents examples of broad-spectrum kinase inhibitors …

[HTML][HTML] Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients

HM Lazarus, ON Koc, SM Devine, P Curtin… - Biology of blood and …, 2005 - Elsevier
Mesenchymal stem cells (MSCs) are found in a variety of tissues, including human bone
marrow; secrete hematopoietic cytokines; support hematopoietic progenitors in vitro; and …

A randomized comparison of nativeEscherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed …

VI Avramis, S Sencer, AP Periclou… - Blood, The Journal …, 2002 - ashpublications.org
For this study, 118 children with standard-risk acute lymphoblastic leukemia (ALL) were
given randomized assignments to receive native or pegylated Escherichia coli asparaginase …

Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers

WI Bensinger, PJ Martin, B Storer, R Clift… - … England Journal of …, 2001 - Mass Medical Soc
Background In recipients of allogeneic hematopoietic-cell transplants, peripheral-blood cells
mobilized with the use of filgrastim (recombinant granulocyte colony-stimulating factor) …

Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide

PV O'donnell, L Luznik, RJ Jones… - Biology of Blood and …, 2002 - tctjournal.org
Cyclophosphamide (Cy) is a potent immunosuppressive agent that is selectively toxic to
lymphocytes proliferating in response to recent antigen stimulation. In animal models, both …

Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009

P Ljungman, M Bregni, M Brune… - Bone marrow …, 2010 - nature.com
Abstract The European Group for Blood and Marrow Transplantation regularly publishes
special reports on the current practice of haematopoietic SCT for haematological diseases …