Association between insulin resistance and the development of cardiovascular disease

V Ormazabal, S Nair, O Elfeky, C Aguayo… - Cardiovascular …, 2018 - Springer
For many years, cardiovascular disease (CVD) has been the leading cause of death around
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …

Gender differences in insulin resistance: new knowledge and perspectives

T Ciarambino, P Crispino, G Guarisco… - Current Issues in …, 2023 - mdpi.com
Insulin resistance is the main mechanism in a whole series of pathological conditions, which
are not only of metabolic interest but also of a systemic type. This phenomenon means that …

[HTML][HTML] Observational study of metformin and risk of mortality in patients hospitalized with Covid-19

CT Bramante, NE Ingraham, TA Murray, S Marmor… - MedRxiv, 2020 - ncbi.nlm.nih.gov
Objective: We sought to identify whether metformin reduced mortality from Covid19 and if
sex specific interactions exist. Design: Retrospective review of de-identified claims from …

Adipose tissue dysfunction and visceral fat are associated with hepatic insulin resistance and severity of NASH even in lean individuals

C Saponaro, S Sabatini, M Gaggini, F Carli… - Liver …, 2022 - Wiley Online Library
Abstract Background & Aims Non‐alcoholic fatty liver disease (NAFLD) is a heterogeneous
disorder, but the factors that determine this heterogeneity remain poorly understood …

The association between regional adiposity, cognitive function, and dementia-related brain changes: a systematic review

E Boccara, S Golan, MS Beeri - Frontiers in Medicine, 2023 - frontiersin.org
Background Adiposity has been previously associated with cognitive impairment and
Alzheimer's disease and related disorders (ADRD). Body mass index (BMI) is the most …

Recent advances in nutraceuticals for the treatment of sarcopenic obesity

YC Kim, SW Ki, H Kim, S Kang, H Kim, G Go - Nutrients, 2023 - mdpi.com
Sarcopenic obesity, low muscle mass, and high body fat are growing health concerns in the
aging population. This review highlights the need for standardized criteria and explores …

Hypothalamic estrogen signaling and adipose tissue metabolism in energy homeostasis

VC Torres Irizarry, Y Jiang, Y He, P Xu - Frontiers in Endocrinology, 2022 - frontiersin.org
Obesity has become a global epidemic, and it is a major risk factor for other metabolic
disorders such as type 2 diabetes and cardiometabolic disease. Accumulating evidence …

More than an anti-diabetic bariatric surgery, metabolic surgery alleviates systemic and local inflammation in obesity

C Zhang, J Zhang, Z Liu, Z Zhou - Obesity Surgery, 2018 - Springer
Obesity, associated with increased risk of type 2 diabetes (T2D), cardiovascular disease,
and hepatic steatosis et al., has become a major global health problem. Recently, obesity …

The genetics of bipolar disorder with obesity and type 2 diabetes

A Miola, E De Filippis, M Veldic, AMC Ho… - Journal of affective …, 2022 - Elsevier
Background Bipolar disorder (BD) presents with high obesity and type 2 diabetes (T2D) and
pathophysiological and phenomenological abnormalities shared with cardiometabolic …

Effect of 12‐month resistance training on changes in abdominal adipose tissue and metabolic variables in patients with prediabetes: a randomized controlled trial

J Yan, X Dai, J Feng, X Yuan, J Li… - Journal of Diabetes …, 2019 - Wiley Online Library
Objective. To examine the effects of resistance training relative to aerobic training on
abdominal adipose tissue and metabolic variables in adults with prediabetes. Methods. 105 …