Insulin resistance changes over time during pregnancy, and in the last half of the pregnancy,
insulin resistance increases considerably and can become severe, especially in women with …

Premature infants are exposed to increased generation of reactive oxygen species, and on
the other hand, they have a deficient antioxidant defense system. Oxidative insult is a salient …

Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood.
Consequently, CP is a public health priority for prevention, but its aetiology has proved …

Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are
particularly relevant in the diagnosis of intestinal dysbiosis. The most common studies of …

Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …

Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …

Preeclampsia (PE), a hypertensive disorder of pregnancy, is increasing as a major
contributor to perinatal and long-term morbidity of mother and offspring. PE is thought to …

Objectives: To improve preclinical drug testing during pregnancy, we developed multiple
microfluidic organ-on-chip (OOC) devices that represent the structure, functions, and …

Background It is well established that obesity is associated with dysregulation of the ratio
between the two major adipokines leptin and adiponectin. Furthermore, it was recently …