Small Molecule Tyrosine Kinase Inhibitors (TKIs) for Glioblastoma Treatment
D Frumento, G Grossi, M Falesiedi, F Musumeci… - International Journal of …, 2024 - mdpi.com
In the last decade, many small molecules, usually characterized by heterocyclic scaffolds,
have been designed and synthesized as tyrosine kinase inhibitors (TKIs). Among them …
have been designed and synthesized as tyrosine kinase inhibitors (TKIs). Among them …
Extracellular Interactors of the IGF System: Impact on Cancer Hallmarks and Therapeutic Approaches
C Mancarella, A Morrione, K Scotlandi - International Journal of …, 2024 - mdpi.com
Dysregulation of the insulin-like growth factor (IGF) system determines the onset of various
pathological conditions, including cancer. Accordingly, therapeutic strategies have been …
pathological conditions, including cancer. Accordingly, therapeutic strategies have been …
Advances in the role of membrane-bound transcription factors in carcinogenesis and therapy
JL Deng, J Zhou, BY Jiang - Discover Oncology, 2024 - Springer
Protein shuttling between the cytoplasm and nucleus is a unique phenomenon in eukaryotic
organisms, integral to various cellular functions. Membrane-bound transcription factors …
organisms, integral to various cellular functions. Membrane-bound transcription factors …