The story of MCF-7 breast cancer cell line: 40 years of experience in research
Ş Comşa, AM Cimpean, M Raica - Anticancer research, 2015 - ar.iiarjournals.org
Breast cancer is the most frequent malignancy in females. Due to its major impact on
population, this disease represents a critical public health problem that requires further …
population, this disease represents a critical public health problem that requires further …
Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer
AB Crujeiras, A Díaz-Lagares, MC Carreira… - Free radical …, 2013 - Taylor & Francis
Diabetes mellitus and breast cancer are two important health problems. Type 2 diabetes
(T2DM) and obesity are closely linked with both being associated with breast cancer …
(T2DM) and obesity are closely linked with both being associated with breast cancer …
Non-coding RNAs: the cancer genome dark matter that matters!
Protein-coding genes comprise only 3% of the human genome, while the genes that are
transcribed into RNAs but do not code for proteins occupy majority of the genome. Once …
transcribed into RNAs but do not code for proteins occupy majority of the genome. Once …
Decoding insulin-like growth factor signaling pathway from a non-coding RNAs perspective: a step towards precision oncology in breast cancer
YA ZeinElAbdeen, A AbdAlSeed… - Journal of Mammary Gland …, 2022 - Springer
Breast cancer (BC) is a highly complex and heterogenous disease. Several oncogenic
signaling pathways drive BC oncogenic activity, thus hindering scientists to unravel the …
signaling pathways drive BC oncogenic activity, thus hindering scientists to unravel the …
MicroRNA regulation of stem cell differentiation and diseases of the bone and adipose tissue: Perspectives on miRNA biogenesis and cellular transcriptome
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression through
targeting and suppression of mRNAs. miRNAs have been under investigation for the past …
targeting and suppression of mRNAs. miRNAs have been under investigation for the past …
Insulin‐like growth factor and epidermal growth factor signaling in breast cancer cell growth: focus on endocrine resistant disease
K Voudouri, A Berdiaki, M Tzardi… - Analytical cellular …, 2015 - Wiley Online Library
Breast cancer is the most common type of cancer for women worldwide with a lifetime risk
amounting to a staggering total of 10%. It is well established that the endogenous synthesis …
amounting to a staggering total of 10%. It is well established that the endogenous synthesis …
Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis
Survival signaling is critical for the metastatic program of cancer cells. The current study
investigated the role of Akt survival proteins in colorectal cancer (CRC) metastasis and …
investigated the role of Akt survival proteins in colorectal cancer (CRC) metastasis and …
IGF-1-mediated PKM2/β-catenin/miR-152 regulatory circuit in breast cancer
YY Wen, WT Liu, HR Sun, X Ge, ZM Shi, M Wang… - Scientific reports, 2017 - nature.com
Dysregulation of miRNAs is important in breast cancer initiation and malignant progression.
Recently we showed that miR-152 downregulation is associated with breast cancer …
Recently we showed that miR-152 downregulation is associated with breast cancer …
Voltage-gated potassium channel blocker 4-aminopyridine induces glioma cell apoptosis by reducing expression of microRNA-10b-5p
Q Ru, W Li, Q Xiong, L Chen, X Tian… - Molecular biology of the …, 2018 - Am Soc Cell Biol
Accumulating evidence has demonstrated that voltage-gated potassium channels (Kv
channels) were associated with regulating cell proliferation and apoptosis in tumor cells. Our …
channels) were associated with regulating cell proliferation and apoptosis in tumor cells. Our …
Insulin-like growth factor 1 differentially affects lithium sensitivity of lymphoblastoid cell lines from lithium responder and non-responder bipolar disorder patients
E Milanesi, A Hadar, E Maffioletti, H Werner… - Journal of Molecular …, 2015 - Springer
Bipolar disorder (BD) is a chronic psychiatric illness with an unknown etiology. Lithium is
considered the cornerstone in the management of BD, though about 50–60% of patients do …
considered the cornerstone in the management of BD, though about 50–60% of patients do …