[HTML][HTML] Development of glioblastoma organoids and their applications in personalized therapy
C Xu, X Yuan, P Hou, Z Li, C Wang… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Glioblastomas (GBMs) are the brain tumors with the highest malignancy and poorest
prognoses. GBM is characterized by high heterogeneity and resistance to drug treatment …
prognoses. GBM is characterized by high heterogeneity and resistance to drug treatment …
Scaffold-based (Matrigel™) 3D culture technique of glioblastoma recovers a patient-like immunosuppressive phenotype
FK Braun, T Rothhammer-Hampl, J Lorenz, S Pohl… - Cells, 2023 - mdpi.com
Conventional 2D cultures are commonly used in cancer research though they come with
limitations such as the lack of microenvironment or reduced cell heterogeneity. In this study …
limitations such as the lack of microenvironment or reduced cell heterogeneity. In this study …
Perivascular invasion of primary human glioblastoma cells in organotypic human brain slices: human cells migrating in human brain
R Ravin, P Suarez-Meade, B Busse, PS Blank… - Journal of neuro …, 2023 - Springer
Introduction Glioblastoma (GBM) is an aggressive primary brain cancer. Lack of effective
therapy is related to its highly invasive nature. GBM invasion has been studied with …
therapy is related to its highly invasive nature. GBM invasion has been studied with …
A novel three-dimensional co-culture model for studying exosome-mediated cell interactions in glioblastoma
K Li, S Du, H Li, Z Li, Q Zhu, Q Peng, B Liao… - Biochimica et Biophysica …, 2025 - Elsevier
Abstract Three-dimensional (3D) cell culture systems provide a larger space for cell
proliferation, which is crucial for simulating cellular behavior and drug responses in the …
proliferation, which is crucial for simulating cellular behavior and drug responses in the …