Ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family members (ENPP1–7)
have been implicated in key biological and pathophysiological processes, including …

Simple Summary A major challenge in treating cancer is when the cancer spreads from its
original site to other parts of the body, a process also known as metastasis. In order to …

PFHxS (Perfluorohexane sulfonic acid) is one of the short-chain perfluoroalkyl substances
(PFASs) which are widely used in many industrial and consumer applications. However …

Severe COVID-19 is characterized by acute respiratory distress syndrome (ARDS)-like
hyperinflammation and endothelial dysfunction, that can lead to respiratory and multi organ …

Background This retrospective, multicenter study evaluated the effect of pemafibrate
treatment on liver function and fibrosis by liver function tests (LFTs) and various fibrotic …

Background & Aims Acute‐on‐chronic liver failure (ACLF) is characterized by systemic
inflammation, monocyte dysfunction, and susceptibility to infection …

Simple Summary Autotaxin (ATX) has been linked with the pathogenesis of several cancers
and especially with breast cancer (BC). BC is one of the most common cancers among …

Autotaxin (ATX) is the only enzyme of the ecto-nucleotide pyrophosphatase/
phosphodiesterase (ENPP2) family with lysophospholipase D (lysoPLD) activity, which is …

The primacy of lipids as essential components of cellular membranes is conserved across
taxonomic domains. In addition to this crucial role as a semi-permeable barrier, lipids are …

Autotaxin (ATX) is a secreted enzyme that produces lysophosphatidate (LPA), which signals
through six G-protein coupled receptors, promoting tumor growth, metastasis, and survival …