DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4)
structures form through self-recognition of guanines into stacked tetrads, and considerable …

Guanine-rich DNA sequences can fold into four-stranded, noncanonical secondary
structures called G-quadruplexes (G4s). G4s were initially considered a structural curiosity …

Metazoan promoters are enriched in secondary DNA structure-forming motifs, such as G-
quadruplexes (G4s). Here we describe 'G4access', an approach to isolate and sequence …

It has been> 20 years since the formation of G-quadruplex (G4) secondary structures in
gene promoters was first linked to the regulation of gene expression. Since then, the …

The response to DNA damage is critical for cellular homeostasis, tumor suppression,
immunity, and gametogenesis. In order to provide an unbiased and global view of the DNA …

Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) is
coupled to altered gene expression. However, approaches that allow us to probe G4s in …

Single-stranded guanine-rich DNA sequences can fold into four-stranded DNA structures
called G-quadruplexes (G4s) that arise from the self-stacking of two or more guanine …

Genomic maps of DNA G-quadruplexes (G4s) can help elucidate the roles that these
secondary structures play in various organisms. Herein, we employ an improved version of a …

Abstract G-quadruplex (G4) structural motifs have been linked to transcription 1, 2,
replication 3 and genome instability 4, 5 and are implicated in cancer and other diseases 6 …

Abstract 'If G-quadruplexes form so readily in vitro, Nature will have found a way of using
them in vivo'(Statement by Aaron Klug over 30 years ago). During the last decade, four …