Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC),
displaying aggressive and metastatic phenotype. Using two different in vitro models, already …

Nanosized vesicles are considered key players in cell to cell communication, thus
influencing physiological and pathological processes, including cancer. Nanovesicles have …

Cellular, inter‐organismal and cross kingdom communication via extracellular vesicles
(EVs) is intensively studied in basic science with high expectation for a large variety of bio …

Bone microenvironment provides growth and survival signals essential for osteosarcoma
(OS) initiation and progression. OS cells regulate communications inside tumor …

Background Multiple myeloma (MM) is a clonal plasma cell malignancy associated with
osteolytic bone disease. Recently, the role of MM-derived exosomes in the …

Bone disease is the most frequent complication in multiple myeloma (MM) resulting in
osteolytic lesions, bone pain, hypercalcemia and renal failure. In MM bone disease the …

Neuroserpin is a serine protease inhibitor identified in a search for proteins implicated in
neuronal axon growth and synapse formation. Since its discovery over 30 years ago, it has …

We show that extracellular vesicles (EVs) released by mesenchymal cells (ie, fibro–
adipogenic progenitors—FAPs) mediate microRNA (miR) transfer to muscle stem cells …

Extracellular vesicles (EVs) play a crucial role as potent signal transducers among cells, with
the potential to operate cross-species and cross-kingdom communication. Nanoalgosomes …

Neuroserpin is a secreted protease inhibitor known to inhibit amyloid formation by the
Alzheimer's beta peptide (Aβ). To test whether this effect was constrained to Aβ, we used a …