APT‐weighted MRI: techniques, current neuro applications, and challenging issues
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …
generates image contrast based predominantly on the amide protons in mobile cellular …
Chemical exchange saturation transfer (CEST) and MR Z-spectroscopy in vivo: a review of theoretical approaches and methods
M Zaiss, P Bachert - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Chemical exchange saturation transfer (CEST) of metabolite protons that undergo exchange
processes with the abundant water pool enables a specific contrast for magnetic resonance …
processes with the abundant water pool enables a specific contrast for magnetic resonance …
Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7 T
Chemical exchange saturation transfer (CEST) is a magnetization transfer (MT) technique to
indirectly detect pools of exchangeable protons through the water signal. CEST MRI has …
indirectly detect pools of exchangeable protons through the water signal. CEST MRI has …
Inverse Z‐spectrum analysis for spillover‐, MT‐, and T1‐corrected steady‐state pulsed CEST‐MRI – application to pH‐weighted MRI of acute stroke
Endogenous chemical exchange saturation transfer (CEST) effects are always diluted by
competing effects, such as direct water proton saturation (spillover) and semi‐solid …
competing effects, such as direct water proton saturation (spillover) and semi‐solid …
Nuts and bolts of chemical exchange saturation transfer MRI
Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast
mechanism that is well suited for molecular imaging studies. This new mechanism can be …
mechanism that is well suited for molecular imaging studies. This new mechanism can be …
CEST signal at 2 ppm (CEST@2ppm) from Z‐spectral fitting correlates with creatine distribution in brain tumor
In general, multiple components such as water direct saturation, magnetization transfer (MT),
chemical exchange saturation transfer (CEST) and aliphatic nuclear Overhauser effect …
chemical exchange saturation transfer (CEST) and aliphatic nuclear Overhauser effect …
MR imaging of the amide‐proton transfer effect and the pH‐insensitive nuclear Overhauser effect at 9.4 T
The amide proton transfer (APT) effect has emerged as a unique endogenous molecular
imaging contrast mechanism with great clinical potentials. However, in vivo quantitative …
imaging contrast mechanism with great clinical potentials. However, in vivo quantitative …
Three‐dimensional amide proton transfer MR imaging of gliomas: initial experience and comparison with gadolinium enhancement
J Zhou, H Zhu, M Lim, L Blair… - Journal of Magnetic …, 2013 - Wiley Online Library
Purpose To investigate the feasibility of a three‐dimensional amide‐proton‐transfer (APT)
imaging sequence with gradient‐and spin‐echo readouts at 3 Tesla in patients with high‐or …
imaging sequence with gradient‐and spin‐echo readouts at 3 Tesla in patients with high‐or …
Exchange‐dependent relaxation in the rotating frame for slow and intermediate exchange–modeling off‐resonant spin‐lock and chemical exchange saturation …
M Zaiss, P Bachert - NMR in Biomedicine, 2013 - Wiley Online Library
Chemical exchange observed by NMR saturation transfer (CEST) and spin‐lock (SL)
experiments provide an MRI contrast by indirect detection of exchanging protons. The …
experiments provide an MRI contrast by indirect detection of exchanging protons. The …
Mapping of amide, amine, and aliphatic peaks in the CEST spectra of murine xenografts at 7 T
KL Desmond, F Moosvi… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose To evaluate the performance of endogenous chemical exchange saturation transfer
(CEST) spectra and derived maps in a longitudinal study of tumor xenografts to ascertain the …
(CEST) spectra and derived maps in a longitudinal study of tumor xenografts to ascertain the …