Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …

Rare diseases (RD) patient registries are powerful instruments that help develop clinical
research, facilitate the planning of appropriate clinical trials, improve patient care, and …

Objectives: Even though today most university hospitals have already implemented
commercial hospital information systems and started to build up comprehensive electronic …

Standards-based, computable knowledge representations for eligibility criteria are
increasingly needed to provide computer-based decision support for automated research …

Big data management for information centralization (ie making data of interest findable) and
integration (ie making related data connectable) in health research is a defining challenge in …

Diagnostic radiologists generally produce unstructured information in the form of images
and narrative text reports. Although designed for human consumption, radiologic reports …

Data from the electronic medical record comprise numerous structured but uncoded ele-
ments, which are not linked to standard terminologies. Reuse of such data for secondary …

Informatics has become an essential component of research in the past few decades,
capitalizing on the efficiency and power of computation to improve the knowledge gained …

Background Use of common data elements (CDEs), conceptually defined as variables that
are operationalized and measured in identical ways across studies, enables comparison of …

General frameworks of the cancer screening process are available, but none directly
compare the process in detail across different organ sites. This limits the ability of medical …