Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis

MD Wang, J Little, J Gomes, NR Cashman, D Krewski - Neurotoxicology, 2017 - Elsevier
Although amyotrophic lateral sclerosis (ALS) was identified as a neurological condition 150
years ago, risk factors related to the onset and progression of ALS remain largely unknown …

[HTML][HTML] Prevalence of amyotrophic lateral sclerosis—United States, 2012–2013

MD Paul Mehta - MMWR. Surveillance Summaries, 2016 - cdc.gov
Abstract Problem/Condition: Amyotrophic lateral sclerosis (ALS), commonly known as Lou
Gehrig's disease, is a progressive and fatal neuromuscular disease for which no cure or …

The Swedish motor neuron disease quality registry

E Longinetti, A Regodón Wallin… - … Lateral Sclerosis and …, 2018 - Taylor & Francis
Objective: We set up the Swedish Motor Neuron Disease (MND) Quality Registry to assure
early diagnosis and high-quality health care for all MND patients (mainly amyotrophic lateral …

A descriptive review of global real world evidence efforts to advance drug discovery and clinical development in amyotrophic lateral sclerosis

SF Cook, T Rhodes, C Schlusser, S Han… - Frontiers in …, 2021 - frontiersin.org
Understanding patient clinical progression is a key gateway to planning effective clinical
trials and ultimately enabling bringing treatments to patients in need. In a rare disease like …

Associations of self-reported occupational exposures and settings to ALS: a case–control study

SA Goutman, J Boss, C Godwin, B Mukherjee… - International Archives of …, 2022 - Springer
Background Environmental exposures contribute to the pathogenesis of amyotrophic lateral
sclerosis (ALS), a fatal and progressive neurological disease. Identification of these …

A mucoadhesive, thermoreversible in situ nasal gel of geniposide for neurodegenerative diseases

Y Wang, S Jiang, H Wang, H Bie - PloS one, 2017 - journals.plos.org
Neurodegenerative diseases are becoming prevalent as the population ages. Geniposide
could inhibit oxidative stress, reduce apoptosis, protect neuron, and has been used for …

Neurodegenerative and psychiatric diseases among families with amyotrophic lateral sclerosis

E Longinetti, D Mariosa, H Larsson, W Ye, C Ingre… - Neurology, 2017 - AAN Enterprises
Objective: To estimate risks of neurodegenerative and psychiatric diseases among patients
with amyotrophic lateral sclerosis (ALS) and their families. Methods: We conducted a …

Digital health solution for monitoring and surveillance of Amyotrophic Lateral Sclerosis in Brazil

IMP Barbalho, ALA Fonseca, F Fernandes… - Frontiers in Public …, 2023 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) is a complex and rare neurodegenerative disease
given its heterogeneity. Despite being known for many years, few countries have accurate …

Case-control study of environmental toxins and risk of amyotrophic lateral sclerosis involving the national ALS registry

EO Talbott, AM Malek, VC Arena, F Wu… - … Lateral Sclerosis and …, 2024 - Taylor & Francis
Objective: Neurotoxic chemicals are suggested in the etiology of amyotrophic lateral
sclerosis (ALS). We examined the association of environmental and occupational risk factors …

[HTML][HTML] Cdc grand rounds: National amyotrophic lateral sclerosis (als) registry impact, challenges, and future directions

P Mehta - MMWR. Morbidity and mortality weekly report, 2017 - cdc.gov
Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, is a rapidly
progressive fatal neurologic disease. Currently, there is no cure for ALS and the available …