Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses
Inflammation is a natural defence response of the immune system against environmental
insult, stress and injury, but hyper-and hypo-inflammatory responses can trigger diseases …
insult, stress and injury, but hyper-and hypo-inflammatory responses can trigger diseases …
Cytokine storm and sepsis disease pathogenesis
BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical
syndrome related to the host response to infection. The severity of infections is due to an …
syndrome related to the host response to infection. The severity of infections is due to an …
Single-cell transcriptome analysis highlights a role for neutrophils and inflammatory macrophages in the pathogenesis of severe COVID-19
Cumulative data link cytokine storms with coronavirus disease 2019 (COVID-19) severity.
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …
Sepsis: pathophysiology and clinical management
JE Gotts, MA Matthay - Bmj, 2016 - bmj.com
Sepsis, severe sepsis, and septic shock represent increasingly severe systemic
inflammatory responses to infection. Sepsis is common in the aging population, and it …
inflammatory responses to infection. Sepsis is common in the aging population, and it …
Connecting aging biology and inflammation in the omics era
KA Walker, N Basisty, DM Wilson… - The Journal of Clinical …, 2022 - Am Soc Clin Investig
Aging is characterized by the accumulation of damage to macromolecules and cell
architecture that triggers a proinflammatory state in blood and solid tissues, termed …
architecture that triggers a proinflammatory state in blood and solid tissues, termed …
The IBD interactome: an integrated view of aetiology, pathogenesis and therapy
HSP De Souza, C Fiocchi, D Iliopoulos - … Reviews Gastroenterology & …, 2017 - nature.com
Crohn's disease and ulcerative colitis are prototypical complex diseases characterized by
chronic and heterogeneous manifestations, induced by interacting environmental, genomic …
chronic and heterogeneous manifestations, induced by interacting environmental, genomic …
Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype
LN Segal, JC Clemente, JCJ Tsay, SB Koralov… - Nature …, 2016 - nature.com
Microaspiration is a common phenomenon in healthy subjects, but its frequency is increased
in chronic inflammatory airway diseases, and its role in inflammatory and immune …
in chronic inflammatory airway diseases, and its role in inflammatory and immune …
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
The acute phase of sepsis is characterized by a strong inflammatory reaction. At later stages
in some patients, immunoparalysis may be encountered, which is associated with a poor …
in some patients, immunoparalysis may be encountered, which is associated with a poor …
The recent progress in animal models of depression
Q Wang, MA Timberlake II, K Prall, Y Dwivedi - Progress in Neuro …, 2017 - Elsevier
Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …
and mortality. Despite the growing number of studies that have emerged, the precise …
The septic heart: current understanding of molecular mechanisms and clinical implications
Septic cardiomyopathy is a key feature of sepsis-associated cardiovascular failure. Despite
the lack of consistent diagnostic criteria, patients typically exhibit ventricular dilatation …
the lack of consistent diagnostic criteria, patients typically exhibit ventricular dilatation …